GSM1017635[Accession] - GEO DataSets

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Items: 4

Select item 2000414571.

Histone H3K9 Methyltransferase G9a Represses PPARγ Expression and Adipogenesis

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platforms:: GPL1261 GPL13112
12 Samples

Download data: BED, CEL

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Accession:: GSE41457

ID:: 200041457

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000414552.

Histone H3K9 Methyltransferase G9a Represses PPARγ Expression and Adipogenesis [ChIP-Seq and RNA-Seq data]

(Submitter supplied) PPARγ promotes adipogenesis while Wnt proteins inhibit adipogenesis. However, the mechanisms that control expression of these positive and negative master regulators of adipogenesis remain incompletely understood. By genome-wide histone methylation profiling in preadipocytes, we find that among gene loci encoding adipogenesis regulators, histone methyltransferase (HMT) G9a-mediated repressive epigenetic mark H3K9me2 is enriched on the entire PPARγ locus. more...