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Items: 1 to 20 of 26

1.

Networks of cultured iPSC-derived neurons reveal the human synaptic activity-regulated adaptive gene program

(Submitter supplied) We studied the synaptic activity-regulated gene expression response in the human genetic background using cultured human iPSC-derived (hiPSCd) neuronal networks and networks of hiPSCd neurons mixed with mouse primary neurons. Our results confirm that genetic changes affect the synaptic activity-regulated gene program, proposing a functional mechanism how they have driven evolution of human cognitive abilities.
Organism:
Mus musculus; Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL19415 GPL11154 GPL16512
22 Samples
Download data: TXT
Series
Accession:
GSE88773
ID:
200088773
2.

Illumina NextSeq 500 (Homo sapiens; Mus musculus)

Organism:
Homo sapiens; Mus musculus
93 Series
1635 Samples
Download data
Platform
Accession:
GPL19415
ID:
100019415
3.

Illumina HiSeq 2000 (Homo sapiens; Mus musculus)

Organism:
Homo sapiens; Mus musculus
20 Series
187 Samples
Download data
Platform
Accession:
GPL16512
ID:
100016512
4.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
5.

co-culture treated with Bic/4AP for 1 h Hs+Ms_Bic-4AP_1h_4

Organism:
Homo sapiens; Mus musculus
Source name:
hiPSC-derived neurons
Platform:
GPL16512
Series:
GSE88773
Download data: TXT
Sample
Accession:
GSM2345410
ID:
302345410
6.

co-culture treated with Bic/4AP for 1 h Hs+Ms_Bic-4AP_1h_3

Organism:
Homo sapiens; Mus musculus
Source name:
hiPSC-derived neurons
Platform:
GPL16512
Series:
GSE88773
Download data: TXT
Sample
Accession:
GSM2345409
ID:
302345409
7.

co-culture treated with Bic/4AP for 1 h Hs+Ms_Bic-4AP_1h_2

Organism:
Mus musculus; Homo sapiens
Source name:
hiPSC-derived neurons
Platform:
GPL16512
Series:
GSE88773
Download data: TXT
Sample
Accession:
GSM2345408
ID:
302345408
8.

co-culture treated with Bic/4AP for 1 h Hs+Ms_Bic-4AP_1h_1

Organism:
Homo sapiens; Mus musculus
Source name:
hiPSC-derived neurons
Platform:
GPL16512
Series:
GSE88773
Download data: TXT
Sample
Accession:
GSM2345407
ID:
302345407
9.

co-culture untreated control Hs+Ms_CNTR_4

Organism:
Mus musculus; Homo sapiens
Source name:
hiPSC-derived neurons
Platform:
GPL16512
Series:
GSE88773
Download data: TXT
Sample
Accession:
GSM2345406
ID:
302345406
10.

co-culture untreated control Hs+Ms_CNTR_3

Organism:
Homo sapiens; Mus musculus
Source name:
hiPSC-derived neurons
Platform:
GPL16512
Series:
GSE88773
Download data: TXT
Sample
Accession:
GSM2345405
ID:
302345405
11.

co-culture untreated control Hs+Ms_CNTR_2

Organism:
Homo sapiens; Mus musculus
Source name:
hiPSC-derived neurons
Platform:
GPL16512
Series:
GSE88773
Download data: TXT
Sample
Accession:
GSM2345404
ID:
302345404
12.

co-culture untreated control Hs+Ms_CNTR_1

Organism:
Mus musculus; Homo sapiens
Source name:
hiPSC-derived neurons
Platform:
GPL16512
Series:
GSE88773
Download data: TXT
Sample
Accession:
GSM2345403
ID:
302345403
13.

co-culture treated with Bic/4AP for 4 h Hs+Ms_Bic-4AP_4h_4

Organism:
Homo sapiens; Mus musculus
Source name:
hiPSC-derived neurons
Platform:
GPL19415
Series:
GSE88773
Download data: TXT
Sample
Accession:
GSM2345413
ID:
302345413
14.

co-culture treated with Bic/4AP for 4 h Hs+Ms_Bic-4AP_4h_3

Organism:
Homo sapiens; Mus musculus
Source name:
hiPSC-derived neurons
Platform:
GPL19415
Series:
GSE88773
Download data: TXT
Sample
Accession:
GSM2345412
ID:
302345412
15.

co-culture treated with Bic/4AP for 4 h Hs+Ms_Bic-4AP_4h_2

Organism:
Homo sapiens; Mus musculus
Source name:
hiPSC-derived neurons
Platform:
GPL19415
Series:
GSE88773
Download data: TXT
Sample
Accession:
GSM2345411
ID:
302345411
16.

hiPSCd neuron-only treated with Bic/4AP for 4 h Hs_Bic-4AP_4h_4

Organism:
Homo sapiens
Source name:
hiPSC-derived neurons
Platform:
GPL11154
Series:
GSE88773
Download data: TXT
Sample
Accession:
GSM2345402
ID:
302345402
17.

hiPSCd neuron-only treated with Bic/4AP for 4 h Hs_Bic-4AP_4h_2

Organism:
Homo sapiens
Source name:
hiPSC-derived neurons
Platform:
GPL11154
Series:
GSE88773
Download data: TXT
Sample
Accession:
GSM2345401
ID:
302345401
18.

hiPSCd neuron-only treated with Bic/4AP for 4 h Hs_Bic-4AP_4h_1

Organism:
Homo sapiens
Source name:
hiPSC-derived neurons
Platform:
GPL11154
Series:
GSE88773
Download data: TXT
Sample
Accession:
GSM2345400
ID:
302345400
19.

hiPSCd neuron-only treated with Bic/4AP for 1 h Hs_Bic-4AP_1h_4

Organism:
Homo sapiens
Source name:
hiPSC-derived neurons
Platform:
GPL11154
Series:
GSE88773
Download data: TXT
Sample
Accession:
GSM2345399
ID:
302345399
20.

hiPSCd neuron-only treated with Bic/4AP for 1 h Hs_Bic-4AP_1h_3

Organism:
Homo sapiens
Source name:
hiPSC-derived neurons
Platform:
GPL11154
Series:
GSE88773
Download data: TXT
Sample
Accession:
GSM2345398
ID:
302345398
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