U.S. flag

An official website of the United States government

Format
Items per page
Sort by

Send to:

Choose Destination

Search results

Items: 8

1.

Runx1 stabilizes the mammary epithelial cell phenotype and prevents epithelial to mesenchymal transition

(Submitter supplied) The Runx1 transcription factor is essential for hematopoietic differentiation and mutations underlie various leukemias. Here we demonstrate a role for Runx1 in the MCF10 cell series model of breast cancer progression. The highest level of Runx1 that occurs in normal like mammary epithelial cells (MCF10A) is decreased in tumorigenic (MCF10AT1) and metastatic (MCF10CA1a) breast cancer cells. We show that depletion of Runx1 in MCF10A cells results in striking changes in cell morphology and induction of epithelial-mesenchymal transition (EMT) via several signaling pathways. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18460
6 Samples
Download data: TXT
2.

Illumina HiSeq 1500 (Homo sapiens)

Platform
Accession:
GPL18460
ID:
100018460
3.

MCF10A_-gf_R3

Organism:
Homo sapiens
Source name:
mammary gland/breast epithelial cell
Platform:
GPL18460
Series:
GSE85857
Download data
Sample
Accession:
GSM2285714
ID:
302285714
4.

MCF10A_-gf_R2

Organism:
Homo sapiens
Source name:
mammary gland/breast epithelial cell
Platform:
GPL18460
Series:
GSE85857
Download data
Sample
Accession:
GSM2285713
ID:
302285713
5.

MCF10A_-gf_R1

Organism:
Homo sapiens
Source name:
mammary gland/breast epithelial cell
Platform:
GPL18460
Series:
GSE85857
Download data
Sample
Accession:
GSM2285712
ID:
302285712
6.

MCF10A_R3

Organism:
Homo sapiens
Source name:
mammary gland/breast epithelial cell
Platform:
GPL18460
Series:
GSE85857
Download data
Sample
Accession:
GSM2285711
ID:
302285711
7.

MCF10A_R2

Organism:
Homo sapiens
Source name:
mammary gland/breast epithelial cell
Platform:
GPL18460
Series:
GSE85857
Download data
Sample
Accession:
GSM2285710
ID:
302285710
8.

MCF10A_R1

Organism:
Homo sapiens
Source name:
mammary gland/breast epithelial cell
Platform:
GPL18460
Series:
GSE85857
Download data
Sample
Accession:
GSM2285709
ID:
302285709
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=GSE85857[Accession]|query=1|qty=2|blobid=MCID_6651ce712ccb3e3e831f850f|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Search details

See more...

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center