GSE85712[Accession] - GEO DataSets - NCBI

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Items: 18

Select item 2000857121.

Physiologic expression of Sf3b1K700E causes impaired erythropoieses, aberrant splicing, and sensitivity to pharmacologic spliceosome modulation

(Submitter supplied) Over 80% of patients with the refractory anemia with ring sideroblasts subtype of myelodysplastic syndrome (MDS) have mutations in Splicing Factor 3B, Subunit 1 (SF3B1). We generated a conditional knock-in mouse model of the most common SF3B1 mutation, Sf3b1K700E. Sf3b1K700E mice develop macrocytic anemia due to a terminal erythroid maturation defect, erythroid dysplasia, and long-term hematopoietic stem cell (LT-HSC) expansion. more...

Organism:: Homo sapiens; Mus musculus

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL11154 GPL19057
15 Samples

Download data: TXT

Series

Accession:: GSE85712

ID:: 200085712

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 1000190572.

Illumina NextSeq 500 (Mus musculus)

Organism:: Mus musculus

10115 Series
291365 Samples

Platform

Accession:: GPL19057

ID:: 100019057

Select item 1000111543.

Illumina HiSeq 2000 (Homo sapiens)

Organism:: Homo sapiens

10505 Series
182944 Samples

Platform

Accession:: GPL11154

ID:: 100011154

Select item 3022820804.

Organism:: Mus musculus

Source name:: Bone Marrow

Platform:: GPL19057
Series:: GSE85712

Download data: TXT

Sample

Accession:: GSM2282080

ID:: 302282080

SRA Run Selector

Select item 3022820795.

Organism:: Mus musculus

Source name:: Bone Marrow

Platform:: GPL19057
Series:: GSE85712

Download data: TXT

Sample

Accession:: GSM2282079

ID:: 302282079

SRA Run Selector

Select item 3022820786.

Organism:: Mus musculus

Source name:: Bone Marrow

Platform:: GPL19057
Series:: GSE85712

Download data: TXT

Sample

Accession:: GSM2282078

ID:: 302282078

SRA Run Selector

Select item 3022820777.

Organism:: Mus musculus

Source name:: Bone Marrow

Platform:: GPL19057
Series:: GSE85712

Download data: TXT

Sample

Accession:: GSM2282077

ID:: 302282077

SRA Run Selector

Select item 3022820768.

Organism:: Mus musculus

Source name:: Bone Marrow

Platform:: GPL19057
Series:: GSE85712

Download data: TXT

Sample

Accession:: GSM2282076

ID:: 302282076

SRA Run Selector

Select item 3022820759.

Organism:: Mus musculus

Source name:: Bone Marrow

Platform:: GPL19057
Series:: GSE85712

Download data: TXT

Sample

Accession:: GSM2282075

ID:: 302282075

SRA Run Selector

Select item 30228208910.

Organism:: Homo sapiens

Source name:: Bone Marrow

Platform:: GPL11154
Series:: GSE85712

Download data: TXT

Sample

Accession:: GSM2282089

ID:: 302282089

SRA Run Selector

Select item 30228208811.

Organism:: Homo sapiens

Source name:: Bone Marrow

Platform:: GPL11154
Series:: GSE85712

Download data: TXT

Sample

Accession:: GSM2282088

ID:: 302282088

SRA Run Selector

Select item 30228208712.

Organism:: Homo sapiens

Source name:: Bone Marrow

Platform:: GPL11154
Series:: GSE85712

Download data: TXT

Sample

Accession:: GSM2282087

ID:: 302282087

SRA Run Selector

Select item 30228208613.

Organism:: Homo sapiens

Source name:: Bone Marrow

Platform:: GPL11154
Series:: GSE85712

Download data: TXT

Sample

Accession:: GSM2282086

ID:: 302282086

SRA Run Selector

Select item 30228208514.

Organism:: Homo sapiens

Source name:: Bone Marrow

Platform:: GPL11154
Series:: GSE85712

Download data: TXT

Sample

Accession:: GSM2282085

ID:: 302282085

SRA Run Selector

Select item 30228208415.

Organism:: Homo sapiens

Source name:: Bone Marrow

Platform:: GPL11154
Series:: GSE85712

Download data: TXT

Sample

Accession:: GSM2282084

ID:: 302282084

SRA Run Selector

Select item 30228208316.

Organism:: Homo sapiens

Source name:: Bone Marrow

Platform:: GPL11154
Series:: GSE85712

Download data: TXT

Sample

Accession:: GSM2282083

ID:: 302282083

SRA Run Selector

Select item 30228208217.

Organism:: Homo sapiens

Source name:: Bone Marrow

Platform:: GPL11154
Series:: GSE85712

Download data: TXT

Sample

Accession:: GSM2282082

ID:: 302282082

SRA Run Selector

Select item 30228208118.

Organism:: Homo sapiens

Source name:: Bone Marrow

Platform:: GPL11154
Series:: GSE85712

Download data: TXT

Sample

Accession:: GSM2282081

ID:: 302282081

SRA Run Selector

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