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Items: 1 to 20 of 31

1.

Niche WNT5A regulates expression of the actin regulatory pathway in regenerating repopulating hematopoietic stem cells

(Submitter supplied) We here show that the niche regulates the quality of the hematopoietic stem cells (HSCs) that are regenerated after transplantation. We find that a reduced level of Wnt5a in the niche regenerates dysfunctional HSCs, which do not successfully engraft secondary recipients. In particular, RNA sequencing shows a dysregulated Zeb1-associated gene expression of multiple genes involved in the small GTPase-dependent actin polymerization pathway. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18480
29 Samples
Download data: TXT
Series
Accession:
GSE84993
ID:
200084993
2.

Illumina HiSeq 1500 (Mus musculus)

Platform
Accession:
GPL18480
ID:
100018480
3.

EC_Wnt5a_18

Organism:
Mus musculus
Source name:
EC niche cell
Platform:
GPL18480
Series:
GSE84993
Download data
Sample
Accession:
GSM2255662
ID:
302255662
4.

OBC_Wnt5a_12

Organism:
Mus musculus
Source name:
OBC niche cell
Platform:
GPL18480
Series:
GSE84993
Download data
Sample
Accession:
GSM2255661
ID:
302255661
5.

MSC_Wnt5a_6

Organism:
Mus musculus
Source name:
MSC niche cell
Platform:
GPL18480
Series:
GSE84993
Download data
Sample
Accession:
GSM2255660
ID:
302255660
6.

EC_Wnt5a_17

Organism:
Mus musculus
Source name:
EC niche cell
Platform:
GPL18480
Series:
GSE84993
Download data
Sample
Accession:
GSM2255659
ID:
302255659
7.

OBC_Wnt5a_11

Organism:
Mus musculus
Source name:
OBC niche cell
Platform:
GPL18480
Series:
GSE84993
Download data
Sample
Accession:
GSM2255658
ID:
302255658
8.

MSC_Wnt5a_5

Organism:
Mus musculus
Source name:
MSC niche cell
Platform:
GPL18480
Series:
GSE84993
Download data
Sample
Accession:
GSM2255657
ID:
302255657
9.

EC_Wnt5a_16

Organism:
Mus musculus
Source name:
EC niche cell
Platform:
GPL18480
Series:
GSE84993
Download data
Sample
Accession:
GSM2255656
ID:
302255656
10.

OBC_Wnt5a_10

Organism:
Mus musculus
Source name:
OBC niche cell
Platform:
GPL18480
Series:
GSE84993
Download data
Sample
Accession:
GSM2255655
ID:
302255655
11.

MSC_Wnt5a_4

Organism:
Mus musculus
Source name:
MSC niche cell
Platform:
GPL18480
Series:
GSE84993
Download data
Sample
Accession:
GSM2255654
ID:
302255654
12.

EC_WT_15

Organism:
Mus musculus
Source name:
EC niche cell
Platform:
GPL18480
Series:
GSE84993
Download data
Sample
Accession:
GSM2255653
ID:
302255653
13.

OBC_WT_9

Organism:
Mus musculus
Source name:
OBC niche cell
Platform:
GPL18480
Series:
GSE84993
Download data
Sample
Accession:
GSM2255652
ID:
302255652
14.

MSC_WT_3

Organism:
Mus musculus
Source name:
MSC niche cell
Platform:
GPL18480
Series:
GSE84993
Download data
Sample
Accession:
GSM2255651
ID:
302255651
15.

EC_WT_14

Organism:
Mus musculus
Source name:
EC niche cell
Platform:
GPL18480
Series:
GSE84993
Download data
Sample
Accession:
GSM2255650
ID:
302255650
16.

OBC_WT_8

Organism:
Mus musculus
Source name:
OBC niche cell
Platform:
GPL18480
Series:
GSE84993
Download data
Sample
Accession:
GSM2255649
ID:
302255649
17.

MSC_WT_2

Organism:
Mus musculus
Source name:
MSC niche cell
Platform:
GPL18480
Series:
GSE84993
Download data
Sample
Accession:
GSM2255648
ID:
302255648
18.

EC_WT_13

Organism:
Mus musculus
Source name:
EC niche cell
Platform:
GPL18480
Series:
GSE84993
Download data
Sample
Accession:
GSM2255647
ID:
302255647
19.

OBC_WT_7

Organism:
Mus musculus
Source name:
OBC niche cell
Platform:
GPL18480
Series:
GSE84993
Download data
Sample
Accession:
GSM2255646
ID:
302255646
20.

MSC_WT_1

Organism:
Mus musculus
Source name:
MSC niche cell
Platform:
GPL18480
Series:
GSE84993
Download data
Sample
Accession:
GSM2255645
ID:
302255645
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Supplemental Content

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