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Items: 11

1.

Genome-wide analysis of DNA hydroxymethylation and methylation during epstein-barr virus infection.

(Submitter supplied) Extensive DNA methylation in promoter regions is observed in gastric cancer with Epstein-barr virus (EBV) infection and EBV infection is the cause to induce this extensive hypermethylaiton phenotype in gastric epithelial cells. From transcriptome analysis, we found that TET2, one of the demethylase enzymes, was downregulated by EBV infection in gastric epithelial cell line MKN7. TET2 was overexpressed in a gastric epithelial cell line, GES1, to see its function and the hydroxymethylation, a byproduct of DNA demethylation, acquired genes by TET2 overexpression and methylation acquired genes by EBV infection were significantly overlapped. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing
Platforms:
GPL18573 GPL18460
8 Samples
Download data: BIGWIG, GTF, XLSX
2.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
3.

Illumina HiSeq 1500 (Homo sapiens)

Platform
Accession:
GPL18460
ID:
100018460
4.

MKN7_EB#1_RNAseq

Organism:
Homo sapiens
Source name:
Gastric cancer cell line
Platform:
GPL18460
Series:
GSE84897
Download data: GTF
Sample
Accession:
GSM2253674
ID:
302253674
5.

MKN7_WT_RNAseq

Organism:
Homo sapiens
Source name:
Gastric cancer cell line
Platform:
GPL18460
Series:
GSE84897
Download data: GTF
Sample
Accession:
GSM2253673
ID:
302253673
6.

GES1_EBV_MeDIPseq

Organism:
Homo sapiens
Source name:
Fetal gastric mucosal cell line
Platform:
GPL18460
Series:
GSE84897
Download data: BIGWIG
Sample
Accession:
GSM2253672
ID:
302253672
7.

GES1_Mock_hMeDIPseq

Organism:
Homo sapiens
Source name:
Fetal gastric mucosal cell line
Platform:
GPL18460
Series:
GSE84897
Download data: XLSX
Sample
Accession:
GSM2253670
ID:
302253670
8.

GES1_TET2OE_hMeDIPseq

Organism:
Homo sapiens
Source name:
Fetal gastric mucosal cell line
Platform:
GPL18460
Series:
GSE84897
Download data: XLSX
Sample
Accession:
GSM2253669
ID:
302253669
9.

MKN7_EB#3_RNAseq

Organism:
Homo sapiens
Source name:
Gastric cancer cell line
Platform:
GPL18573
Series:
GSE84897
Download data: GTF
Sample
Accession:
GSM2253676
ID:
302253676
10.

MKN7_EB#2_RNAseq

Organism:
Homo sapiens
Source name:
Gastric cancer cell line
Platform:
GPL18573
Series:
GSE84897
Download data: GTF
Sample
Accession:
GSM2253675
ID:
302253675
11.

GES1_WT_MeDIPseq

Organism:
Homo sapiens
Source name:
Fetal gastric mucosal cell line
Platform:
GPL18573
Series:
GSE84897
Download data: BIGWIG
Sample
Accession:
GSM2253671
ID:
302253671
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Supplemental Content

db=gds|term=GSE84897[Accession]|query=1|qty=2|blobid=MCID_65e17e720b2ad618bb5ec390|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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