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Items: 11

1.

A Druggable TCF4- and BRD4-dependent Transcriptional Network Sustains Malignancy in Blastic Plasmacytoid Dendritic Cell Neoplasm (ATAC-Seq)

(Submitter supplied) Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an aggressive and largely incurable hematologic malignancy originating from plasmacytoid dendritic cells (pDCs). Using RNA interference screening, we identified the E-box transcription factor TCF4 as a master regulator of the BPDCN oncogenic program. TCF4 served as a faithful diagnostic marker of BPDCN, and its downregulation caused the loss of the BPDCN-specific expression program and apoptosis. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL18573
9 Samples
Download data: WIG
Series
Accession:
GSE84623
ID:
200084623

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina NextSeq 500 (Homo sapiens)

Organism:
Homo sapiens
12849 Series
347275 Samples
Download data
Platform
Accession:
GPL18573
ID:
100018573

3.

BPDCN Patient-1 ATAC-Seq

Organism:
Homo sapiens
Source name:
BPDCN Patient-1
Platform:
GPL18573
Series:
GSE84623
Download data: WIG
Sample
Accession:
GSM2243041
ID:
302243041

SRA Run Selector

4.

cDCs Donor-2 ATAC-Seq

Organism:
Homo sapiens
Source name:
cDCs Donor-2
Platform:
GPL18573
Series:
GSE84623
Download data: WIG
Sample
Accession:
GSM2243040
ID:
302243040

SRA Run Selector

5.

pDCs Donor-2 ATAC-Seq

Organism:
Homo sapiens
Source name:
pDCs Donor-2
Platform:
GPL18573
Series:
GSE84623
Download data: WIG
Sample
Accession:
GSM2243039
ID:
302243039

SRA Run Selector

6.

cDCs Donor-1 ATAC-Seq

Organism:
Homo sapiens
Source name:
cDCs Donor-1
Platform:
GPL18573
Series:
GSE84623
Download data: WIG
Sample
Accession:
GSM2243038
ID:
302243038

SRA Run Selector

7.

pDCs Donor-1 ATAC-Seq

Organism:
Homo sapiens
Source name:
pDCs Donor-1
Platform:
GPL18573
Series:
GSE84623
Download data: WIG
Sample
Accession:
GSM2243037
ID:
302243037

SRA Run Selector

8.

MOLM-14 ATAC-Seq

Organism:
Homo sapiens
Source name:
MOLM-14
Platform:
GPL18573
Series:
GSE84623
Download data: WIG
Sample
Accession:
GSM2243036
ID:
302243036

SRA Run Selector

9.

HL-60 ATAC-Seq

Organism:
Homo sapiens
Source name:
HL-60
Platform:
GPL18573
Series:
GSE84623
Download data: WIG
Sample
Accession:
GSM2243035
ID:
302243035

SRA Run Selector

10.

Gen2.2 ATAC-Seq

Organism:
Homo sapiens
Source name:
Gen2.2
Platform:
GPL18573
Series:
GSE84623
Download data: WIG
Sample
Accession:
GSM2243034
ID:
302243034

SRA Run Selector

11.

Cal-1 ATAC-Seq

Organism:
Homo sapiens
Source name:
Cal-1
Platform:
GPL18573
Series:
GSE84623
Download data: WIG
Sample
Accession:
GSM2243033
ID:
302243033

SRA Run Selector

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