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Items: 11

1.

A Druggable TCF4- and BRD4-dependent Transcriptional Network Sustains Malignancy in Blastic Plasmacytoid Dendritic Cell Neoplasm (ATAC-Seq)

(Submitter supplied) Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an aggressive and largely incurable hematologic malignancy originating from plasmacytoid dendritic cells (pDCs). Using RNA interference screening, we identified the E-box transcription factor TCF4 as a master regulator of the BPDCN oncogenic program. TCF4 served as a faithful diagnostic marker of BPDCN, and its downregulation caused the loss of the BPDCN-specific expression program and apoptosis. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL18573
9 Samples
Download data: WIG
Series
Accession:
GSE84623
ID:
200084623
2.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
3.

BPDCN Patient-1 ATAC-Seq

Organism:
Homo sapiens
Source name:
BPDCN Patient-1
Platform:
GPL18573
Series:
GSE84623
Download data: WIG
Sample
Accession:
GSM2243041
ID:
302243041
4.

cDCs Donor-2 ATAC-Seq

Organism:
Homo sapiens
Source name:
cDCs Donor-2
Platform:
GPL18573
Series:
GSE84623
Download data: WIG
Sample
Accession:
GSM2243040
ID:
302243040
5.

pDCs Donor-2 ATAC-Seq

Organism:
Homo sapiens
Source name:
pDCs Donor-2
Platform:
GPL18573
Series:
GSE84623
Download data: WIG
Sample
Accession:
GSM2243039
ID:
302243039
6.

cDCs Donor-1 ATAC-Seq

Organism:
Homo sapiens
Source name:
cDCs Donor-1
Platform:
GPL18573
Series:
GSE84623
Download data: WIG
Sample
Accession:
GSM2243038
ID:
302243038
7.

pDCs Donor-1 ATAC-Seq

Organism:
Homo sapiens
Source name:
pDCs Donor-1
Platform:
GPL18573
Series:
GSE84623
Download data: WIG
Sample
Accession:
GSM2243037
ID:
302243037
8.

MOLM-14 ATAC-Seq

Organism:
Homo sapiens
Source name:
MOLM-14
Platform:
GPL18573
Series:
GSE84623
Download data: WIG
Sample
Accession:
GSM2243036
ID:
302243036
9.

HL-60 ATAC-Seq

Organism:
Homo sapiens
Source name:
HL-60
Platform:
GPL18573
Series:
GSE84623
Download data: WIG
Sample
Accession:
GSM2243035
ID:
302243035
10.

Gen2.2 ATAC-Seq

Organism:
Homo sapiens
Source name:
Gen2.2
Platform:
GPL18573
Series:
GSE84623
Download data: WIG
Sample
Accession:
GSM2243034
ID:
302243034
11.

Cal-1 ATAC-Seq

Organism:
Homo sapiens
Source name:
Cal-1
Platform:
GPL18573
Series:
GSE84623
Download data: WIG
Sample
Accession:
GSM2243033
ID:
302243033
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Supplemental Content

db=gds|term=GSE84623[Accession]|query=1|qty=2|blobid=MCID_65ddf13c22cedd048f66e0c4|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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