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Items: 8

1.

Loss of Uhrf1 in neural stem cells leads to activation of retroviral elements and delayed neurodegeneration [RRBS]

(Submitter supplied) In order to understand if early epigenetic mechanisms instruct the long-term behaviour of neural stem cells (NSCs) and their progeny, we examined the protein Uhrf1 as it is highly expressed in NSCs of the developing brain and rapidly downregulated upon differentiation. Conditional deletion of Uhrf1 in the developing cerebral cortex resulted in rather normal proliferation and neurogenesis but severe postnatal neurodegeneration. more...
Organism:
Mus musculus
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL18480
6 Samples
Download data: TXT
Series
Accession:
GSE84549
ID:
200084549
2.

Illumina HiSeq 1500 (Mus musculus)

Platform
Accession:
GPL18480
ID:
100018480
3.

Uhrf1_cKO_3

Organism:
Mus musculus
Source name:
E16 full cortex
Platform:
GPL18480
Series:
GSE84549 GSE84550
Download data: TXT
Sample
Accession:
GSM2241746
ID:
302241746
4.

Uhrf1_cKO_2

Organism:
Mus musculus
Source name:
E16 full cortex
Platform:
GPL18480
Series:
GSE84549 GSE84550
Download data: TXT
Sample
Accession:
GSM2241745
ID:
302241745
5.

Uhrf1_cKO_1

Organism:
Mus musculus
Source name:
E16 full cortex
Platform:
GPL18480
Series:
GSE84549 GSE84550
Download data: TXT
Sample
Accession:
GSM2241744
ID:
302241744
6.

Uhrf1_Heterozygous_3

Organism:
Mus musculus
Source name:
E16 full cortex
Platform:
GPL18480
Series:
GSE84549 GSE84550
Download data: TXT
Sample
Accession:
GSM2241743
ID:
302241743
7.

Uhrf1_Heterozygous_2

Organism:
Mus musculus
Source name:
E16 full cortex
Platform:
GPL18480
Series:
GSE84549 GSE84550
Download data: TXT
Sample
Accession:
GSM2241742
ID:
302241742
8.

Uhrf1_Heterozygous_1

Organism:
Mus musculus
Source name:
E16 full cortex
Platform:
GPL18480
Series:
GSE84549 GSE84550
Download data: TXT
Sample
Accession:
GSM2241741
ID:
302241741
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Supplemental Content

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