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Items: 14

1.

Induction of DNA methylation changes in primary human hepatocytes by valproic acid

(Submitter supplied) Valproic acid (VPA) is a very potent anti-cancer and neuro-protective drug. However, exposure to VPA may cause accumulation of lipids in the liver which could result in the development of steatosis. As VPA is a fatty acid analogue, most of the performed studies focus on inhibition of the mitochondrial b-oxidation pathway as the possible mode of action. However, investigations exploring the contribution of other processes in particular by using whole genome studies in a relevant human liver model are limited. more...
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platform:
GPL16284
12 Samples
Download data: PAIR, TXT
Series
Accession:
GSE84189
ID:
200084189
2.

NimbleGen Human DNA Methylation 2.1M Deluxe Promoter Array [100929_HG19_Deluxe_Prom_Meth_HX1]

(Submitter supplied) Build: HG19, NCBI 37 Protocol: see manufacturer's website
Organism:
Homo sapiens
16 Series
175 Samples
Download data: GFF, NCD, NDF, POS
Platform
Accession:
GPL16284
ID:
100016284
3.

Primary human hepatocyte 5 days 15 mM valproic acid and 3 days medium replicate 3

Organism:
Homo sapiens
Source name:
input DNA from human primary hepatocytes (channel 1) medip DNA from human primary hepatocytes (channel 2)
Platform:
GPL16284
Series:
GSE84189 GSE84250
Download data: PAIR
Sample
Accession:
GSM2228815
ID:
302228815
4.

Primary human hepatocyte 5 days 15 mM valproic acid and 3 days medium replicate 2

Organism:
Homo sapiens
Source name:
input DNA from human primary hepatocytes (channel 1) medip DNA from human primary hepatocytes (channel 2)
Platform:
GPL16284
Series:
GSE84189 GSE84250
Download data: PAIR
Sample
Accession:
GSM2228814
ID:
302228814
5.

Primary human hepatocyte 5 days 15 mM valproic acid and 3 days medium replicate 1

Organism:
Homo sapiens
Source name:
input DNA from human primary hepatocytes (channel 1) medip DNA from human primary hepatocytes (channel 2)
Platform:
GPL16284
Series:
GSE84189 GSE84250
Download data: PAIR
Sample
Accession:
GSM2228813
ID:
302228813
6.

Primary human hepatocyte 8 days control replicate 3

Organism:
Homo sapiens
Source name:
input DNA from human primary hepatocytes (channel 1) medip DNA from human primary hepatocytes (channel 2)
Platform:
GPL16284
Series:
GSE84189 GSE84250
Download data: PAIR
Sample
Accession:
GSM2228812
ID:
302228812
7.

Primary human hepatocyte 8 days control replicate 2

Organism:
Homo sapiens
Source name:
input DNA from human primary hepatocytes (channel 1) medip DNA from human primary hepatocytes (channel 2)
Platform:
GPL16284
Series:
GSE84189 GSE84250
Download data: PAIR
Sample
Accession:
GSM2228811
ID:
302228811
8.

Primary human hepatocyte 8 days control replicate 1

Organism:
Homo sapiens
Source name:
input DNA from human primary hepatocytes (channel 1) medip DNA from human primary hepatocytes (channel 2)
Platform:
GPL16284
Series:
GSE84189 GSE84250
Download data: PAIR
Sample
Accession:
GSM2228810
ID:
302228810
9.

Primary human hepatocyte 5 days 15 mM valproic acid replicate 3

Organism:
Homo sapiens
Source name:
input DNA from human primary hepatocytes (channel 1) medip DNA from human primary hepatocytes (channel 2)
Platform:
GPL16284
Series:
GSE84189 GSE84250
Download data: PAIR
Sample
Accession:
GSM2228809
ID:
302228809
10.

Primary human hepatocyte 5 days 15 mM valproic acid replicate 2

Organism:
Homo sapiens
Source name:
input DNA from human primary hepatocytes (channel 1) medip DNA from human primary hepatocytes (channel 2)
Platform:
GPL16284
Series:
GSE84189 GSE84250
Download data: PAIR
Sample
Accession:
GSM2228808
ID:
302228808
11.

Primary human hepatocyte 5 days 15 mM valproic acid replicate 1

Organism:
Homo sapiens
Source name:
input DNA from human primary hepatocytes (channel 1) medip DNA from human primary hepatocytes (channel 2)
Platform:
GPL16284
Series:
GSE84189 GSE84250
Download data: PAIR
Sample
Accession:
GSM2228807
ID:
302228807
12.

Primary human hepatocyte 5 days control replicate 3

Organism:
Homo sapiens
Source name:
input DNA from human primary hepatocytes (channel 1) medip DNA from human primary hepatocytes (channel 2)
Platform:
GPL16284
Series:
GSE84189 GSE84250
Download data: PAIR
Sample
Accession:
GSM2228806
ID:
302228806
13.

Primary human hepatocyte 5 days control replicate 2

Organism:
Homo sapiens
Source name:
input DNA from human primary hepatocytes (channel 1) medip DNA from human primary hepatocytes (channel 2)
Platform:
GPL16284
Series:
GSE84189 GSE84250
Download data: PAIR
Sample
Accession:
GSM2228805
ID:
302228805
14.

Primary human hepatocyte 5 days control replicate 1

Organism:
Homo sapiens
Source name:
input DNA from human primary hepatocytes (channel 1) medip DNA from human primary hepatocytes (channel 2)
Platform:
GPL16284
Series:
GSE84189 GSE84250
Download data: PAIR
Sample
Accession:
GSM2228804
ID:
302228804
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Supplemental Content

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