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Items: 13

1.

PAX3-FOXO1 requires BRD4 to drive oncogene addiction in RMS cells [RNA-seq]

(Submitter supplied) The fusion transcription factor PAX3-FOXO1 drives oncogenesis in a subset of rhabdomyosarcomas, however the mechanisms by which it remodels chromatin are unknown. We find PAX3-FOXO1 reprograms the cis-regulatory landscape by inducing super enhancers (SEs), in collaboration with master transcription factors MYOG, MYOD and MYCN. This myogenic SE circuitry is consistent across cell lines and primary tumors. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL11154 GPL18573
10 Samples
Download data: FPKM_TRACKING
2.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
3.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
4.

RH41 DMSO 6hr rep1 RNA-seq

Organism:
Homo sapiens
Source name:
RMS cell line, PAX3-FOXO1
Platform:
GPL11154
Series:
GSE83724 GSE83728
Download data: FPKM_TRACKING
Sample
Accession:
GSM2214068
ID:
302214068
5.

RH41 DMSO 6hr rep2 RNA-seq

Organism:
Homo sapiens
Source name:
RMS cell line, PAX3-FOXO1
Platform:
GPL11154
Series:
GSE83724 GSE83728
Download data: FPKM_TRACKING
Sample
Accession:
GSM2214067
ID:
302214067
6.

RH41 JQ1 500nM 6hr RNA-seq

Organism:
Homo sapiens
Source name:
RMS cell line, PAX3-FOXO1
Platform:
GPL11154
Series:
GSE83724 GSE83728
Download data: FPKM_TRACKING
Sample
Accession:
GSM2214065
ID:
302214065
7.

RH41 JQ1 5000nM 6hr RNA-seq

Organism:
Homo sapiens
Source name:
RMS cell line, PAX3-FOXO1
Platform:
GPL11154
Series:
GSE83724 GSE83728
Download data: FPKM_TRACKING
Sample
Accession:
GSM2214064
ID:
302214064
8.

7250-PAX3-FOXO1 RNA-seq

Organism:
Homo sapiens
Source name:
Fibroblast cell line, PAX3-FOXO1 vector added
Platform:
GPL11154
Series:
GSE83724 GSE83728
Download data: FPKM_TRACKING
Sample
Accession:
GSM2214062
ID:
302214062
9.

7250-empty RNA-seq

Organism:
Homo sapiens
Source name:
Fibroblast cell line, empty vector added
Platform:
GPL11154
Series:
GSE83724 GSE83728
Download data: FPKM_TRACKING
Sample
Accession:
GSM2214061
ID:
302214061
10.

RH4 shscramble 48hr RNA-seq

Organism:
Homo sapiens
Source name:
RMS cell line, PAX3-FOXO1
Platform:
GPL18573
Series:
GSE83724 GSE83728
Download data: FPKM_TRACKING
Sample
Accession:
GSM2214070
ID:
302214070
11.

RH4 shPAX3FOXO1 48hr RNA-seq

Organism:
Homo sapiens
Source name:
RMS cell line, PAX3-FOXO1
Platform:
GPL18573
Series:
GSE83724 GSE83728
Download data: FPKM_TRACKING
Sample
Accession:
GSM2214069
ID:
302214069
12.

RH4 DMSO 6hr RNA-seq

Organism:
Homo sapiens
Source name:
RMS cell line, PAX3-FOXO1
Platform:
GPL18573
Series:
GSE83724 GSE83728
Download data: FPKM_TRACKING
Sample
Accession:
GSM2214066
ID:
302214066
13.

RH4 JQ1 500nM 6hr RNA-seq

Organism:
Homo sapiens
Source name:
RMS cell line, PAX3-FOXO1
Platform:
GPL18573
Series:
GSE83724 GSE83728
Download data: FPKM_TRACKING
Sample
Accession:
GSM2214063
ID:
302214063
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Supplemental Content

db=gds|term=GSE83724[Accession]|query=1|qty=2|blobid=MCID_6670a2e2909a3d46ade806ae|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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