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Items: 10

1.

ChIP-seq for identifying molecules associated with epithelial-mesenchymal transition and acquired resistance to ALK inhibitors

(Submitter supplied) Treatment with ALK tyrosine kinase inhibitors often elicits profound initial antitumor responses in ALK fusion-positive patients with lung adenocarcinoma. However, patients invariably develop acquired resistance to ALK inhibitors. In this study, we aimed to identify molecular events that limit the response to ALK inhibition using genetic and epigenetic approaches. To identify novel mechanisms of acquired resistance to ALK inhibitors, we established in vitro models of acquired resistance to ceritinib using H3122 cell. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL18573
8 Samples
Download data: BEDGRAPH
Series
Accession:
GSE81482
ID:
200081482
2.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
3.

H3122_LR_Pano_H3K27ac_ChIP-seq

Organism:
Homo sapiens
Source name:
H3122 lung cancer cell line
Platform:
GPL18573
Series:
GSE81482 GSE81487
Download data: BEDGRAPH
Sample
Accession:
GSM2154741
ID:
302154741
4.

H3122_LR_Pano_input_ChIP-seq

Organism:
Homo sapiens
Source name:
H3122 lung cancer cell line
Platform:
GPL18573
Series:
GSE81482 GSE81487
Download data: BEDGRAPH
Sample
Accession:
GSM2154740
ID:
302154740
5.

H3122_LR_H3K4me1_ChIP-seq

Organism:
Homo sapiens
Source name:
H3122 lung cancer cell line
Platform:
GPL18573
Series:
GSE81482 GSE81487
Download data: BEDGRAPH
Sample
Accession:
GSM2154739
ID:
302154739
6.

H3122_LR_H3K27Ac_ChIP-seq

Organism:
Homo sapiens
Source name:
H3122 lung cancer cell line
Platform:
GPL18573
Series:
GSE81482 GSE81487
Download data: BEDGRAPH
Sample
Accession:
GSM2154738
ID:
302154738
7.

H3122_LR_input_ChIP-seq

Organism:
Homo sapiens
Source name:
H3122 lung cancer cell line
Platform:
GPL18573
Series:
GSE81482 GSE81487
Download data: BEDGRAPH
Sample
Accession:
GSM2154737
ID:
302154737
8.

H3122_H3K4me1_ChIP-seq

Organism:
Homo sapiens
Source name:
H3122 lung cancer cell line
Platform:
GPL18573
Series:
GSE81482 GSE81487
Download data: BEDGRAPH
Sample
Accession:
GSM2154736
ID:
302154736
9.

H3122_H3K27Ac_ChIP-seq

Organism:
Homo sapiens
Source name:
H3122 lung cancer cell line
Platform:
GPL18573
Series:
GSE81482 GSE81487
Download data: BEDGRAPH
Sample
Accession:
GSM2154735
ID:
302154735
10.

H3122_input_ChIP-seq

Organism:
Homo sapiens
Source name:
H3122 lung cancer cell line
Platform:
GPL18573
Series:
GSE81482 GSE81487
Download data: BEDGRAPH
Sample
Accession:
GSM2154734
ID:
302154734
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Supplemental Content

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