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Items: 8

1.

BET bromodomain proteins function as master transcription elongation factors independent of CDK9 recruitment [NET-seq]

(Submitter supplied) Cancer arises from the malignant interplay between oncogenic signaling and cell specification. Transcriptionally activated stem, growth and survival programs reshape an epigenomic identity defined by a transcriptional core regulatory circuitry. To study and disrupt oncogenic transcription, we first created inhibitors of BET bromodomains. Selective antagonism of oncogenic transcriptional signaling arises from bromodomain-specific activity. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Other
Platform:
GPL18573
6 Samples
Download data: BEDGRAPH
Series
Accession:
GSE79271
ID:
200079271
2.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
3.

NET-seq dBET6 Rep2

Organism:
Homo sapiens
Source name:
dBET6
Platform:
GPL18573
Series:
GSE79271 GSE79290
Download data: BEDGRAPH
Sample
Accession:
GSM2090430
ID:
302090430
4.

NET-seq dBET6 Rep1

Organism:
Homo sapiens
Source name:
dBET6
Platform:
GPL18573
Series:
GSE79271 GSE79290
Download data: BEDGRAPH
Sample
Accession:
GSM2090429
ID:
302090429
5.

NET-seq JQ1 Rep2

Organism:
Homo sapiens
Source name:
JQ1
Platform:
GPL18573
Series:
GSE79271 GSE79290
Download data: BEDGRAPH
Sample
Accession:
GSM2090428
ID:
302090428
6.

NET-seq JQ1 Rep1

Organism:
Homo sapiens
Source name:
JQ1
Platform:
GPL18573
Series:
GSE79271 GSE79290
Download data: BEDGRAPH
Sample
Accession:
GSM2090427
ID:
302090427
7.

NET-seq DMSO Rep2

Organism:
Homo sapiens
Source name:
DMSO
Platform:
GPL18573
Series:
GSE79271 GSE79290
Download data: BEDGRAPH
Sample
Accession:
GSM2090426
ID:
302090426
8.

NET-seq DMSO Rep1

Organism:
Homo sapiens
Source name:
DMSO
Platform:
GPL18573
Series:
GSE79271 GSE79290
Download data: BEDGRAPH
Sample
Accession:
GSM2090425
ID:
302090425
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Supplemental Content

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