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Items: 14

1.

DSBCapture: in situ capture and direct sequencing of dsDNA breaks

(Submitter supplied) Double-strand DNA breaks (DSBs) continuously arise and are a source of mutations and chromosomal rearrangements. Here, we present DSBCapture, a sequencing-based method that captures DSBs in situ and directly maps these at single nucleotide resolution enabling the study of DSB origin. DSBCapture shows substantially increased sensitivity and data yield compared to other methods. Employing DSBCapture, we uncovered a striking relationship between DSBs and elevated transcription within nucleosome-depleted chromatin.
Organism:
Homo sapiens
Type:
Other; Expression profiling by high throughput sequencing
Platforms:
GPL18573 GPL15520
11 Samples
Download data: BED, BEDGRAPH, NARROWPEAK, TDF, TXT
2.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
3.

Illumina MiSeq (Homo sapiens)

Platform
Accession:
GPL15520
ID:
100015520
4.

EcoRV_restriction_enzyme

Organism:
Homo sapiens
Source name:
EcoRV_restriction_enzyme
Platform:
GPL15520
Series:
GSE78172
Download data: BEDGRAPH
Sample
Accession:
GSM2068753
ID:
302068753
5.

HEK_GIBCO_4

Organism:
Homo sapiens
Source name:
HEK
Platform:
GPL18573
Series:
GSE78172
Download data
Sample
Accession:
GSM2222371
ID:
302222371
6.

HEK_GIBCO_3

Organism:
Homo sapiens
Source name:
HEK
Platform:
GPL18573
Series:
GSE78172
Download data
Sample
Accession:
GSM2222370
ID:
302222370
7.

HEK_GIBCO_2

Organism:
Homo sapiens
Source name:
HEK
Platform:
GPL18573
Series:
GSE78172
Download data
Sample
Accession:
GSM2222369
ID:
302222369
8.

HEK_GIBCO_1

Organism:
Homo sapiens
Source name:
HEK
Platform:
GPL18573
Series:
GSE78172
Download data
Sample
Accession:
GSM2222368
ID:
302222368
9.

NHEK_break_seq_lower_input_rep1

Organism:
Homo sapiens
Source name:
NHEK_break_seq_lower_input
Platform:
GPL18573
Series:
GSE78172
Download data: BEDGRAPH
Sample
Accession:
GSM2160171
ID:
302160171
10.

NHEK_bless_seq_rep2

Organism:
Homo sapiens
Source name:
NHEK_bless_seq
Platform:
GPL18573
Series:
GSE78172
Download data: BEDGRAPH
Sample
Accession:
GSM2068758
ID:
302068758
11.

NHEK_bless_seq_rep1

Organism:
Homo sapiens
Source name:
NHEK_bless_seq
Platform:
GPL18573
Series:
GSE78172
Download data: BEDGRAPH
Sample
Accession:
GSM2068757
ID:
302068757
12.

NHEK_break_seq_rep2

Organism:
Homo sapiens
Source name:
NHEK_break_seq
Platform:
GPL18573
Series:
GSE78172
Download data: BEDGRAPH
Sample
Accession:
GSM2068756
ID:
302068756
13.

NHEK_break_seq_rep1

Organism:
Homo sapiens
Source name:
NHEK_break_seq
Platform:
GPL18573
Series:
GSE78172
Download data: BEDGRAPH
Sample
Accession:
GSM2068755
ID:
302068755
14.

AID-DlvA_AsiSI_restriction_enzyme

Organism:
Homo sapiens
Source name:
AID-DlvA_AsiSI_restriction_enzyme
Platform:
GPL18573
Series:
GSE78172
Download data: BEDGRAPH
Sample
Accession:
GSM2068754
ID:
302068754
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Supplemental Content

db=gds|term=GSE78172[Accession]|query=1|qty=2|blobid=MCID_65e73ab003778d6c486743bb|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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