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Items: 1 to 20 of 25

1.

Different promoter affinities account for specificity in MYC-dependent gene regulation

(Submitter supplied) Enhanced expression of the MYC transcription factor is observed in the majority of tumors. Two seemingly conflicting models have been proposed for its function: one proposes that MYC enhances expression of all genes, while the other model suggests gene-specific regulation. Here, we have explored the hypothesis that specific gene expression profiles arise since promoters differ in affinity for MYC and high-affinity promoters are fully occupied by physiological levels of MYC. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL10999 GPL18573
22 Samples
Download data: TXT, WIG
2.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
3.

Illumina Genome Analyzer IIx (Homo sapiens)

Platform
Accession:
GPL10999
ID:
100010999
4.

ChIPseq_input

Organism:
Homo sapiens
Source name:
U2OS cells
Platform:
GPL10999
Series:
GSE77356
Download data: WIG
Sample
Accession:
GSM2050641
ID:
302050641
5.

ChIPseq_MYC_Dox0.0

Organism:
Homo sapiens
Source name:
U2OS cells
Platform:
GPL10999
Series:
GSE77356
Download data: WIG
Sample
Accession:
GSM2050640
ID:
302050640
6.

ChIPseq_MYC_Dox1.0

Organism:
Homo sapiens
Source name:
U2OS cells
Platform:
GPL10999
Series:
GSE77356
Download data: WIG
Sample
Accession:
GSM2050639
ID:
302050639
7.

RNAseq_titration_Dox0.0_rep2

Organism:
Homo sapiens
Source name:
U2OS cells
Platform:
GPL10999
Series:
GSE77356
Download data
Sample
Accession:
GSM2050638
ID:
302050638
8.

RNAseq_titration_Dox1.0_rep2

Organism:
Homo sapiens
Source name:
U2OS cells
Platform:
GPL10999
Series:
GSE77356
Download data
Sample
Accession:
GSM2050637
ID:
302050637
9.

RNAseq_titration_Dox0.1_rep2

Organism:
Homo sapiens
Source name:
U2OS cells
Platform:
GPL10999
Series:
GSE77356
Download data
Sample
Accession:
GSM2050636
ID:
302050636
10.

RNAseq_titration_Dox0.05_rep2

Organism:
Homo sapiens
Source name:
U2OS cells
Platform:
GPL10999
Series:
GSE77356
Download data
Sample
Accession:
GSM2050635
ID:
302050635
11.

RNAseq_titration_Dox0.01_rep2

Organism:
Homo sapiens
Source name:
U2OS cells
Platform:
GPL10999
Series:
GSE77356
Download data
Sample
Accession:
GSM2050634
ID:
302050634
12.

RNAseq_titration_Dox0.0_rep1

Organism:
Homo sapiens
Source name:
U2OS cells
Platform:
GPL10999
Series:
GSE77356
Download data
Sample
Accession:
GSM2050633
ID:
302050633
13.

RNAseq_titration_Dox1.0_rep1

Organism:
Homo sapiens
Source name:
U2OS cells
Platform:
GPL10999
Series:
GSE77356
Download data
Sample
Accession:
GSM2050632
ID:
302050632
14.

RNAseq_titration_Dox0.1_rep1

Organism:
Homo sapiens
Source name:
U2OS cells
Platform:
GPL10999
Series:
GSE77356
Download data
Sample
Accession:
GSM2050631
ID:
302050631
15.

RNAseq_titration_Dox0.05_rep1

Organism:
Homo sapiens
Source name:
U2OS cells
Platform:
GPL10999
Series:
GSE77356
Download data
Sample
Accession:
GSM2050630
ID:
302050630
16.

RNAseq_titration_Dox0.01_rep1

Organism:
Homo sapiens
Source name:
U2OS cells
Platform:
GPL10999
Series:
GSE77356
Download data
Sample
Accession:
GSM2050629
ID:
302050629
17.

RNAseq_depletion_siMYC_rep3

Organism:
Homo sapiens
Source name:
U2OS cells
Platform:
GPL10999
Series:
GSE77356
Download data
Sample
Accession:
GSM2050628
ID:
302050628
18.

RNAseq_depletion_siCTR_rep3

Organism:
Homo sapiens
Source name:
U2OS cells
Platform:
GPL10999
Series:
GSE77356
Download data
Sample
Accession:
GSM2050627
ID:
302050627
19.

RNAseq_depletion_siMYC_rep2

Organism:
Homo sapiens
Source name:
U2OS cells
Platform:
GPL10999
Series:
GSE77356
Download data
Sample
Accession:
GSM2050626
ID:
302050626
20.

RNAseq_depletion_siCTR_rep2

Organism:
Homo sapiens
Source name:
U2OS cells
Platform:
GPL10999
Series:
GSE77356
Download data
Sample
Accession:
GSM2050625
ID:
302050625
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Supplemental Content

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