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Items: 8

1.

Comparison of Bach2-tdRFP high expression and low expression NP-specific IgG1 light zone GC B cells

(Submitter supplied) Despite the importance of memory B cells for protection from recurrent infection, how these cells are selected during germinal center (GC) reactions remains unclear. We show here that light zone (LZ) GC B cells with lower affinity BCRs express a less CD40 signature and relatively high levels of Bach2, being prone to enter the memory B cell pool. We also find that Bach2 contributes to memory B cell generation in a Blimp-1-independent manner and that its higher expression confers on LZ GC cells a more advantage for entering the memory B cell compartment. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18480
6 Samples
Download data: TXT
Series
Accession:
GSE77319
ID:
200077319
2.

Illumina HiSeq 1500 (Mus musculus)

Platform
Accession:
GPL18480
ID:
100018480
3.

Bach2-tdRFP high 3

Organism:
Mus musculus
Source name:
IgG1 LZ GC B cells, high Bach2-tdRFP
Platform:
GPL18480
Series:
GSE77319
Download data: TXT
Sample
Accession:
GSM2049195
ID:
302049195
4.

Bach2-tdRFP high 2

Organism:
Mus musculus
Source name:
IgG1 LZ GC B cells, high Bach2-tdRFP
Platform:
GPL18480
Series:
GSE77319
Download data: TXT
Sample
Accession:
GSM2049194
ID:
302049194
5.

Bach2-tdRFP high 1

Organism:
Mus musculus
Source name:
IgG1 LZ GC B cells, high Bach2-tdRFP
Platform:
GPL18480
Series:
GSE77319
Download data: TXT
Sample
Accession:
GSM2049193
ID:
302049193
6.

Bach2-tdRFP low 3

Organism:
Mus musculus
Source name:
IgG1 LZ GC B cells, low Bach2-tdRFP
Platform:
GPL18480
Series:
GSE77319
Download data: TXT
Sample
Accession:
GSM2049192
ID:
302049192
7.

Bach2-tdRFP low 2

Organism:
Mus musculus
Source name:
IgG1 LZ GC B cells, low Bach2-tdRFP
Platform:
GPL18480
Series:
GSE77319
Download data: TXT
Sample
Accession:
GSM2049191
ID:
302049191
8.

Bach2-tdRFP low 1

Organism:
Mus musculus
Source name:
IgG1 LZ GC B cells, low Bach2-tdRFP
Platform:
GPL18480
Series:
GSE77319
Download data: TXT
Sample
Accession:
GSM2049190
ID:
302049190
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Supplemental Content

db=gds|term=GSE77319[Accession]|query=1|qty=2|blobid=MCID_66519e192ccb3e3e831bf3a1|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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