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Items: 13

1.

RNA-seq transcriptonal profiling in partial hepatectomy liver tissues in Arid1a WT and liver specific KO mice.

(Submitter supplied) Arid1a is the subunit of SWI/SNF complex, which was reported to guide SWI/SNF to DNA. Here, we found that loss of Arid1a in the liver results in improved liver regeneration after partial hepatectomy.Genome-wide analysis showed that after hepatectomy,loss of Arid1a reduces the recruitment and activity of E2F4 on target promoters, resulting in expression programs that favor regeneration during injury.RNAseq shows transcriptional profiling in WT and Arid1a LKO livers pre- and post-hepatectomy, which confirmed the E2F4 target genes and cell cycle genes were upregulated after hepatectomy.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL19057 GPL17021
10 Samples
Download data: TXT, XLS
Series
Accession:
GSE76926
ID:
200076926
2.

Illumina NextSeq 500 (Mus musculus)

Platform
Accession:
GPL19057
ID:
100019057
3.

Illumina HiSeq 2500 (Mus musculus)

Platform
Accession:
GPL17021
ID:
100017021
4.

RNAseq_postPHX_KO_rep3

Organism:
Mus musculus
Source name:
frozen post-hepatectomy liver tissue
Platform:
GPL19057
Series:
GSE76926 GSE76935
Download data
Sample
Accession:
GSM2040952
ID:
302040952
5.

RNAseq_postPHX_KO_rep2

Organism:
Mus musculus
Source name:
frozen post-hepatectomy liver tissue
Platform:
GPL19057
Series:
GSE76926 GSE76935
Download data
Sample
Accession:
GSM2040951
ID:
302040951
6.

RNAseq_postPHX_KO_rep1

Organism:
Mus musculus
Source name:
frozen post-hepatectomy liver tissue
Platform:
GPL19057
Series:
GSE76926 GSE76935
Download data
Sample
Accession:
GSM2040950
ID:
302040950
7.

RNAseq_postPHX_WT_rep3

Organism:
Mus musculus
Source name:
frozen post-hepatectomy liver tissue
Platform:
GPL19057
Series:
GSE76926 GSE76935
Download data
Sample
Accession:
GSM2040949
ID:
302040949
8.

RNAseq_postPHX_WT_rep2

Organism:
Mus musculus
Source name:
frozen post-hepatectomy liver tissue
Platform:
GPL19057
Series:
GSE76926 GSE76935
Download data
Sample
Accession:
GSM2040948
ID:
302040948
9.

RNAseq_postPHX_WT_rep1

Organism:
Mus musculus
Source name:
frozen post-hepatectomy liver tissue
Platform:
GPL19057
Series:
GSE76926 GSE76935
Download data
Sample
Accession:
GSM2040947
ID:
302040947
10.

RNAseq_prePHX_KO_rep2

Organism:
Mus musculus
Source name:
frozen pre-hepatectomy liver tissue
Platform:
GPL17021
Series:
GSE76926 GSE76935
Download data: XLS
Sample
Accession:
GSM2040946
ID:
302040946
11.

RNAseq_prePHX_KO_rep1

Organism:
Mus musculus
Source name:
frozen pre-hepatectomy liver tissue
Platform:
GPL17021
Series:
GSE76926 GSE76935
Download data: XLS
Sample
Accession:
GSM2040945
ID:
302040945
12.

RNAseq_prePHX_WT_rep2

Organism:
Mus musculus
Source name:
frozen pre-hepatectomy liver tissue
Platform:
GPL17021
Series:
GSE76926 GSE76935
Download data: XLS
Sample
Accession:
GSM2040944
ID:
302040944
13.

RNAseq_prePHX_WT_rep1

Organism:
Mus musculus
Source name:
frozen pre-hepatectomy liver tissue
Platform:
GPL17021
Series:
GSE76926 GSE76935
Download data: XLS
Sample
Accession:
GSM2040943
ID:
302040943
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Supplemental Content

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