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Items: 1 to 20 of 25

1.

Expression profiling of MCF-7 cells with inducible LMO4 and DN-Clim expression

(Submitter supplied) The nuclear LIM-only protein LMO4 is upregulated in breast cancer, especially estrogen receptor negative tumors, and its overexpression in mice leads to hyperplasia and tumor formation. Here, we show that deletion of LMO4 in the mammary glands of mice leads to impaired lobuloalveolar development due to decreased epithelial cell proliferation. With the goal of discovering potential LMO4-target genes, we also developed a conditional expression system in MCF-7 cells for both LMO4 and a dominant negative (DN) form of its co-regulator, Co-factor of LIM domains (Clim/Ldb/Nli). more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Datasets:
GDS2787 GDS2788 GDS2789
Platforms:
GPL96 GPL97 GPL570
18 Samples
Download data: CEL
Series
Accession:
GSE7382
ID:
200007382
2.
Full record GDS2789

LIM homeobox protein cofactor dominant negative form effect on breast cancer cell line

Analysis of breast cancer MCF-7 cells after the induction of expression of a dominant negative form of the cofactor of LIM domains (CLIM), a co-regulator of the nuclear LIM only protein 4 (LMO4). LMO4 is upregulated in breast cancer. Results provide insight into the role of LMO4 in tumor formation.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 protocol sets
Platform:
GPL570
Series:
GSE7382
6 Samples
Download data: CEL
DataSet
Accession:
GDS2789
ID:
2789
3.
Full record GDS2788

LIM-only protein 4 induction effect on breast cancer cell line (HG-U133B)

Analysis of breast cancer MCF-7 cells following the induction of expression of nuclear LIM-only protein 4 (LMO4). LMO4 is upregulated in breast cancer. Results provide insight into the role of LMO4 in promoting tumor formation.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 protocol sets
Platform:
GPL97
Series:
GSE7382
6 Samples
Download data: CEL
DataSet
Accession:
GDS2788
ID:
2788
4.
Full record GDS2787

LIM-only protein 4 induction effect on breast cancer cell line (HG-U133A)

Analysis of breast cancer MCF-7 cells following the induction of expression of nuclear LIM-only protein 4 (LMO4). LMO4 is upregulated in breast cancer. Results provide insight into the role of LMO4 in promoting tumor formation.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 protocol sets
Platform:
GPL96
Series:
GSE7382
6 Samples
Download data: CEL
DataSet
Accession:
GDS2787
ID:
2787
5.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...
Organism:
Homo sapiens
602 DataSets
5642 Series
61 Related Platforms
171144 Samples
Download data
Platform
Accession:
GPL570
ID:
100000570
6.

[HG-U133A] Affymetrix Human Genome U133A Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 June 24, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The U133 set includes 2 arrays with a total of 44928 entries and was indexed 29-Jan-2002. more...
Organism:
Homo sapiens
364 DataSets
1125 Series
11 Related Platforms
42430 Samples
Download data
Platform
Accession:
GPL96
ID:
100000096
7.

[HG-U133B] Affymetrix Human Genome U133B Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 21, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The U133 set includes 2 arrays with a total of 44928 entries and was indexed 29-Jan-2002. more...
Organism:
Homo sapiens
51 DataSets
165 Series
2 Related Platforms
7917 Samples
Download data
Platform
Accession:
GPL97
ID:
100000097
8.

MCF7 LMO4 high Replicate3

Organism:
Homo sapiens
Source name:
MCF7-LMO4-TetOff cells
Platform:
GPL96
Series:
GSE7382
Dataset:
GDS2787
Download data: CEL
Sample
Accession:
GSM177582
ID:
300177582
9.

MCF7 LMO4 high Replicate2

Organism:
Homo sapiens
Source name:
MCF7-LMO4-TetOff cells
Platform:
GPL96
Series:
GSE7382
Dataset:
GDS2787
Download data: CEL
Sample
Accession:
GSM177581
ID:
300177581
10.

MCF7 LMO4 high Replicate1

Organism:
Homo sapiens
Source name:
MCF7-LMO4-TetOff cells
Platform:
GPL96
Series:
GSE7382
Dataset:
GDS2787
Download data: CEL
Sample
Accession:
GSM177580
ID:
300177580
11.

MCF7 LMO4 low Replicate3

Organism:
Homo sapiens
Source name:
MCF7-LMO4-TetOff cells
Platform:
GPL96
Series:
GSE7382
Dataset:
GDS2787
Download data: CEL
Sample
Accession:
GSM177579
ID:
300177579
12.

MCF7 LMO4 low Replicate2

Organism:
Homo sapiens
Source name:
MCF7-LMO4-TetOff cells
Platform:
GPL96
Series:
GSE7382
Dataset:
GDS2787
Download data: CEL
Sample
Accession:
GSM177578
ID:
300177578
13.

MCF7 LMO4 low Replicate1

Organism:
Homo sapiens
Source name:
MCF7-LMO4-TetOff cells
Platform:
GPL96
Series:
GSE7382
Dataset:
GDS2787
Download data: CEL
Sample
Accession:
GSM177577
ID:
300177577
14.

MCF7 LMO4 high Replicate3B

Organism:
Homo sapiens
Source name:
MCF7-LMO4-TetOff cells
Platform:
GPL97
Series:
GSE7382
Dataset:
GDS2788
Download data: CEL
Sample
Accession:
GSM177588
ID:
300177588
15.

MCF7 LMO4 high Replicate2B

Organism:
Homo sapiens
Source name:
MCF7-LMO4-TetOff cells
Platform:
GPL97
Series:
GSE7382
Dataset:
GDS2788
Download data: CEL
Sample
Accession:
GSM177587
ID:
300177587
16.

MCF7 LMO4 high Replicate1B

Organism:
Homo sapiens
Source name:
MCF7-LMO4-TetOff cells
Platform:
GPL97
Series:
GSE7382
Dataset:
GDS2788
Download data: CEL
Sample
Accession:
GSM177586
ID:
300177586
17.

MCF7 LMO4 low Replicate3B

Organism:
Homo sapiens
Source name:
MCF7-LMO4-TetOff cells
Platform:
GPL97
Series:
GSE7382
Dataset:
GDS2788
Download data: CEL
Sample
Accession:
GSM177585
ID:
300177585
18.

MCF7 LMO4 low Replicate2B

Organism:
Homo sapiens
Source name:
MCF7-LMO4-TetOff cells
Platform:
GPL97
Series:
GSE7382
Dataset:
GDS2788
Download data: CEL
Sample
Accession:
GSM177584
ID:
300177584
19.

MCF7 LMO4 low Replicate1B

Organism:
Homo sapiens
Source name:
MCF7-LMO4-TetOff cells
Platform:
GPL97
Series:
GSE7382
Dataset:
GDS2788
Download data: CEL
Sample
Accession:
GSM177583
ID:
300177583
20.

MCF7 DN-CLIM high Replicate3

Organism:
Homo sapiens
Source name:
MCF7-DN-CLIM-TetOff cells
Platform:
GPL570
Series:
GSE7382
Dataset:
GDS2789
Download data: CEL
Sample
Accession:
GSM177594
ID:
300177594
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db=gds|term=GSE7382[Accession]|query=1|qty=2|blobid=MCID_66213d3a36ac342f8a9a163d|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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