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Items: 14

1.

Profiles of ribosome-associated mRNAs regulated by expression of wild-type (WT) or R534H variant of DDX3 with or without Sodium Arsenite treatment [Ribo-Seq]

(Submitter supplied) By using ribosome profiling, we demonstrate that catalytic activity of the RNA helicase DDX3 is generally required for mediating translation repression under stress. Intriguingly, however, a cancer-related DDX3 variant DDX3 R534H selectively preserves translation of genes encoding core nucleosome components. Additionally, DDX3 variants also shift ORF usage on select genes, such as RPLP1 and stress-response factors as an added mechanism of translation regulation during stress. more...
Organism:
Homo sapiens
Type:
Other
Platform:
GPL16791
12 Samples
Download data: BW
Series
Accession:
GSE70802
ID:
200070802

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 2500 (Homo sapiens)

Organism:
Homo sapiens
12241 Series
349855 Samples
Download data
Platform
Accession:
GPL16791
ID:
100016791

3.

DDX3 R534H ribosome profiling with sodium arsenite rep2

Organism:
Homo sapiens
Source name:
HEK293
Platform:
GPL16791
Series:
GSE70802 GSE70804
Download data: BW
Sample
Accession:
GSM1819228
ID:
301819228

SRA Run Selector

4.

DDX3 WT ribosome profiling with sodium arsenite rep2

Organism:
Homo sapiens
Source name:
HEK293
Platform:
GPL16791
Series:
GSE70802 GSE70804
Download data: BW
Sample
Accession:
GSM1819227
ID:
301819227

SRA Run Selector

5.

Rluc control ribosome profiling with sodium arsenite rep2

Organism:
Homo sapiens
Source name:
HEK293
Platform:
GPL16791
Series:
GSE70802 GSE70804
Download data: BW
Sample
Accession:
GSM1819226
ID:
301819226

SRA Run Selector

6.

DDX3 R534H ribosome profiling rep2

Organism:
Homo sapiens
Source name:
HEK293
Platform:
GPL16791
Series:
GSE70802 GSE70804
Download data: BW
Sample
Accession:
GSM1819225
ID:
301819225

SRA Run Selector

7.

DDX3 WT ribosome profiling rep2

Organism:
Homo sapiens
Source name:
HEK293
Platform:
GPL16791
Series:
GSE70802 GSE70804
Download data: BW
Sample
Accession:
GSM1819224
ID:
301819224

SRA Run Selector

8.

Rluc control ribosome profiling rep2

Organism:
Homo sapiens
Source name:
HEK293
Platform:
GPL16791
Series:
GSE70802 GSE70804
Download data: BW
Sample
Accession:
GSM1819223
ID:
301819223

SRA Run Selector

9.

DDX3 R534H ribosome profiling with sodium arsenite rep1

Organism:
Homo sapiens
Source name:
HEK293
Platform:
GPL16791
Series:
GSE70802 GSE70804
Download data: BW
Sample
Accession:
GSM1819222
ID:
301819222

SRA Run Selector

10.

DDX3 WT ribosome profiling with sodium arsenite rep1

Organism:
Homo sapiens
Source name:
HEK293
Platform:
GPL16791
Series:
GSE70802 GSE70804
Download data: BW
Sample
Accession:
GSM1819221
ID:
301819221

SRA Run Selector

11.

Rluc control ribosome profiling with sodium arsenite rep1

Organism:
Homo sapiens
Source name:
HEK293
Platform:
GPL16791
Series:
GSE70802 GSE70804
Download data: BW
Sample
Accession:
GSM1819220
ID:
301819220

SRA Run Selector

12.

DDX3 R534H ribosome profiling rep1

Organism:
Homo sapiens
Source name:
HEK293
Platform:
GPL16791
Series:
GSE70802 GSE70804
Download data: BW
Sample
Accession:
GSM1819219
ID:
301819219

SRA Run Selector

13.

DDX3 WT ribosome profiling rep1

Organism:
Homo sapiens
Source name:
HEK293
Platform:
GPL16791
Series:
GSE70802 GSE70804
Download data: BW
Sample
Accession:
GSM1819218
ID:
301819218

SRA Run Selector

14.

Rluc control ribosome profiling rep1

Organism:
Homo sapiens
Source name:
HEK293
Platform:
GPL16791
Series:
GSE70802 GSE70804
Download data: BW
Sample
Accession:
GSM1819217
ID:
301819217

SRA Run Selector

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