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Items: 10

1.

Single cell RNA-Seq of Hira-KO and control MII oocytes [Gdf9-Cre+]

(Submitter supplied) The integrity of chromatin, which provides a dynamic template for all DNA related processes in eukaryotes, is maintained through replication dependent and independent assembly pathways. To address the role of replication independent histone deposition, we deleted the histone H3.3 chaperone Hira in developing mouse oocytes. We show that chromatin of non-replicative developing oocytes is highly dynamic, and that lack of continuous H3.3/H4 deposition alters chromatin structure, resulting in increased DNase I sensitivity, the accumulation of DNA damage, and, ultimately, a severe fertility phenotype. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17021
8 Samples
Download data: XLSX
Series
Accession:
GSE66931
ID:
200066931
2.

Illumina HiSeq 2500 (Mus musculus)

Platform
Accession:
GPL17021
ID:
100017021
3.

Hira-KO6_RNA-Seq [Gdf9-Cre+]

Organism:
Mus musculus
Source name:
MII oocyte, Hira-KO
Platform:
GPL17021
Series:
GSE66931 GSE73382
Download data
Sample
Accession:
GSM1634470
ID:
301634470
4.

Hira-KO5_RNA-Seq [Gdf9-Cre+]

Organism:
Mus musculus
Source name:
MII oocyte, Hira-KO
Platform:
GPL17021
Series:
GSE66931 GSE73382
Download data
Sample
Accession:
GSM1634469
ID:
301634469
5.

Hira-KO3_RNA-Seq [Gdf9-Cre+]

Organism:
Mus musculus
Source name:
MII oocyte, Hira-KO
Platform:
GPL17021
Series:
GSE66931 GSE73382
Download data
Sample
Accession:
GSM1634468
ID:
301634468
6.

Hira-KO1_RNA-Seq [Gdf9-Cre+]

Organism:
Mus musculus
Source name:
MII oocyte, Hira-KO
Platform:
GPL17021
Series:
GSE66931 GSE73382
Download data
Sample
Accession:
GSM1634467
ID:
301634467
7.

Hira-WT5_RNA-Seq [Gdf9-Cre+]

Organism:
Mus musculus
Source name:
MII oocyte, Hira-WT
Platform:
GPL17021
Series:
GSE66931 GSE73382
Download data
Sample
Accession:
GSM1634466
ID:
301634466
8.

Hira-WT4_RNA-Seq [Gdf9-Cre+]

Organism:
Mus musculus
Source name:
MII oocyte, Hira-WT
Platform:
GPL17021
Series:
GSE66931 GSE73382
Download data
Sample
Accession:
GSM1634465
ID:
301634465
9.

Hira-WT2_RNA-Seq [Gdf9-Cre+]

Organism:
Mus musculus
Source name:
MII oocyte, Hira-WT
Platform:
GPL17021
Series:
GSE66931 GSE73382
Download data
Sample
Accession:
GSM1634464
ID:
301634464
10.

Hira-WT1_RNA-Seq [Gdf9-Cre+]

Organism:
Mus musculus
Source name:
MII oocyte, Hira-WT
Platform:
GPL17021
Series:
GSE66931 GSE73382
Download data
Sample
Accession:
GSM1634463
ID:
301634463
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Supplemental Content

db=gds|term=GSE66931[Accession]|query=1|qty=2|blobid=MCID_6672c71c6a1d573bf6835825|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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