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Items: 8

1.

Paraoxonase 2 Serves a Proapopotic Function in Mouse and Human Cells in Response to the Pseudomonas aeruginosa Quorum-Sensing Molecule N-(3-oxododecanoyl)-Homoserine Lactone.

(Submitter supplied) Pseudomonas aeruginosa use quorum-sensing molecules, including N-(3-oxododecanoyl)-homoserine lactone (C12), for intercellular communication. C12 activated apoptosis in mouse embryo fibroblasts (MEF) from both wild type (WT) and Bax/Bak double knock-out mice (WT MEF and DKO MEF that were responsive to C12, DKOR MEF): nuclei fragmented; mitochondrial membrane potential (∆ψmito) depolarized; Ca2+ was released from the endoplasmic reticulum (ER), increasing cytosolic [Ca2+] (Cacyto); caspase 3/7 was activated. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17021
6 Samples
Download data: TXT
Series
Accession:
GSE65935
ID:
200065935
2.

Illumina HiSeq 2500 (Mus musculus)

Platform
Accession:
GPL17021
ID:
100017021
3.

DKONR_MEF2

Organism:
Mus musculus
Source name:
Mouse embryo fibroblast 
Platform:
GPL17021
Series:
GSE65935
Download data
Sample
Accession:
GSM1611445
ID:
301611445
4.

DKONR_MEF1

Organism:
Mus musculus
Source name:
Mouse embryo fibroblast 
Platform:
GPL17021
Series:
GSE65935
Download data
Sample
Accession:
GSM1611444
ID:
301611444
5.

DKOR_MEF2

Organism:
Mus musculus
Source name:
Mouse embryo fibroblast 
Platform:
GPL17021
Series:
GSE65935
Download data
Sample
Accession:
GSM1611443
ID:
301611443
6.

DKOR_MEF1

Organism:
Mus musculus
Source name:
Mouse embryo fibroblast 
Platform:
GPL17021
Series:
GSE65935
Download data
Sample
Accession:
GSM1611442
ID:
301611442
7.

WT_MEF2

Organism:
Mus musculus
Source name:
Mouse embryo fibroblast 
Platform:
GPL17021
Series:
GSE65935
Download data
Sample
Accession:
GSM1611441
ID:
301611441
8.

WT_MEF1

Organism:
Mus musculus
Source name:
Mouse embryo fibroblast 
Platform:
GPL17021
Series:
GSE65935
Download data
Sample
Accession:
GSM1611440
ID:
301611440
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Supplemental Content

db=gds|term=GSE65935[Accession]|query=1|qty=2|blobid=MCID_666ca4256e9d376f2337f5d2|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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