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1.

Insights into the combined action of SAHA (vorinostat) and Mithramycin A in Sézary cells through gene expression profiling

(Submitter supplied) Suberoyl Anilide Hydroxamic Acid (SAHA), also named under Vorinostat, is an inhibitor of class I and II histone deacetylases (HDACi) approved by the USA Food and Drug Administration (FDA) for the treatment of advanced and refractory cutaneous T-cell lymphomas (CTCL). Its limited efficacy led to its use in various combination therapies. Given that SAHA modifies the expression of many genes under control of Sp1 (or Sp3) transcription factors, we investigated here its association to the FDA-approved anticancer antibiotic Mithramycin (MitA), a direct inhibitor of the binding of Sp1 family factors to GC-rich DNA promoters. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL13607
48 Samples
Download data: TXT
Series
Accession:
GSE64119
ID:
200064119
2.

Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Feature Number version)

(Submitter supplied) SurePrint G3 Human GE 8x60K Microarray Arrays of this design have barcodes that begin with 16028004 or 2528004. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. The ID column represents the Agilent Feature Extraction feature number. more...
Organism:
Homo sapiens
233 Series
2 Related Platforms
3749 Samples
Download data: TXT
Platform
Accession:
GPL13607
ID:
100013607
3.

SS_P4 cells_SAHA+MitA_rep.3

Organism:
Homo sapiens
Source name:
SS cells_SAHA+MitA_24 h
Platform:
GPL13607
Series:
GSE64119
Download data: TXT
Sample
Accession:
GSM1564782
ID:
301564782
4.

SS_P4 cells_SAHA+MitA_rep.2

Organism:
Homo sapiens
Source name:
SS cells_SAHA+MitA_24 h
Platform:
GPL13607
Series:
GSE64119
Download data: TXT
Sample
Accession:
GSM1564781
ID:
301564781
5.

SS_P4 cells_SAHA+MitA_rep.1

Organism:
Homo sapiens
Source name:
SS cells_SAHA+MitA_24 h
Platform:
GPL13607
Series:
GSE64119
Download data: TXT
Sample
Accession:
GSM1564780
ID:
301564780
6.

SS_P3 cells_SAHA+MitA_rep.3

Organism:
Homo sapiens
Source name:
SS cells_SAHA+MitA_24 h
Platform:
GPL13607
Series:
GSE64119
Download data: TXT
Sample
Accession:
GSM1564779
ID:
301564779
7.

SS_P3 cells_SAHA+MitA_rep.2

Organism:
Homo sapiens
Source name:
SS cells_SAHA+MitA_24 h
Platform:
GPL13607
Series:
GSE64119
Download data: TXT
Sample
Accession:
GSM1564778
ID:
301564778
8.

SS_P3 cells_SAHA+MitA_rep.1

Organism:
Homo sapiens
Source name:
SS cells_SAHA+MitA_24 h
Platform:
GPL13607
Series:
GSE64119
Download data: TXT
Sample
Accession:
GSM1564777
ID:
301564777
9.

SS_P2 cells_SAHA+MitA_rep.3

Organism:
Homo sapiens
Source name:
SS cells_SAHA+MitA_24 h
Platform:
GPL13607
Series:
GSE64119
Download data: TXT
Sample
Accession:
GSM1564776
ID:
301564776
10.

SS_P2 cells_SAHA+MitA_rep.2

Organism:
Homo sapiens
Source name:
SS cells_SAHA+MitA_24 h
Platform:
GPL13607
Series:
GSE64119
Download data: TXT
Sample
Accession:
GSM1564775
ID:
301564775
11.

SS_P2 cells_SAHA+MitA_rep.1

Organism:
Homo sapiens
Source name:
SS cells_SAHA+MitA_24 h
Platform:
GPL13607
Series:
GSE64119
Download data: TXT
Sample
Accession:
GSM1564774
ID:
301564774
12.

SS_P1 cells_SAHA+MitA_rep.3

Organism:
Homo sapiens
Source name:
SS cells_SAHA+MitA_24 h
Platform:
GPL13607
Series:
GSE64119
Download data: TXT
Sample
Accession:
GSM1564773
ID:
301564773
13.

SS_P1 cells_SAHA+MitA_rep.2

Organism:
Homo sapiens
Source name:
SS cells_SAHA+MitA_24 h
Platform:
GPL13607
Series:
GSE64119
Download data: TXT
Sample
Accession:
GSM1564772
ID:
301564772
14.

SS_P1 cells_SAHA+MitA_rep.1

Organism:
Homo sapiens
Source name:
SS cells_SAHA+MitA_24 h
Platform:
GPL13607
Series:
GSE64119
Download data: TXT
Sample
Accession:
GSM1564771
ID:
301564771
15.

SS_P4 cells_MitA_rep.3

Organism:
Homo sapiens
Source name:
SS cells_MitA_24 h
Platform:
GPL13607
Series:
GSE64119
Download data: TXT
Sample
Accession:
GSM1564770
ID:
301564770
16.

SS_P4 cells_MitA_rep.2

Organism:
Homo sapiens
Source name:
SS cells_MitA_24 h
Platform:
GPL13607
Series:
GSE64119
Download data: TXT
Sample
Accession:
GSM1564769
ID:
301564769
17.

SS_P4 cells_MitA_rep.1

Organism:
Homo sapiens
Source name:
SS cells_MitA_24 h
Platform:
GPL13607
Series:
GSE64119
Download data: TXT
Sample
Accession:
GSM1564768
ID:
301564768
18.

SS_P3 cells_MitA_rep.3

Organism:
Homo sapiens
Source name:
SS cells_MitA_24 h
Platform:
GPL13607
Series:
GSE64119
Download data: TXT
Sample
Accession:
GSM1564767
ID:
301564767
19.

SS_P3 cells_MitA_rep.2

Organism:
Homo sapiens
Source name:
SS cells_MitA_24 h
Platform:
GPL13607
Series:
GSE64119
Download data: TXT
Sample
Accession:
GSM1564766
ID:
301564766
20.

SS_P3 cells_MitA_rep.1

Organism:
Homo sapiens
Source name:
SS cells_MitA_24 h
Platform:
GPL13607
Series:
GSE64119
Download data: TXT
Sample
Accession:
GSM1564765
ID:
301564765
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