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Items: 1 to 20 of 57

1.

Divergent transcriptional activation by glucocorticoids in mouse and human macrophages is the result of gain and loss of enhancers

(Submitter supplied) Macrophages are amongst the major targets of glucocorticoids (GC) as therapeutic anti-inflammatory agents. Here we show that GC treatment of mouse and human macrophages initiates a cascade of induced gene expression including many anti-inflammatory genes. Inducible binding of the glucocorticoid receptor (GR) was detected at candidate enhancers in the vicinity of induced genes in both species and this was strongly associated with canonical GR binding motifs. more...
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing
4 related Platforms
52 Samples
Download data: CEL
Series
Accession:
GSE61881
ID:
200061881
2.

[HT_MG-430_PM] Affymetrix HT MG-430 PM Array Plate

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html Protocol: see manufacturer's web site
Organism:
Mus musculus
13 DataSets
285 Series
9 Related Platforms
6973 Samples
Download data
Platform
Accession:
GPL11180
ID:
100011180
3.

[HT_HG-U133_Plus_PM] Affymetrix HT HG-U133+ PM Array Plate

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html Annotations derived from HT_HG-U133_Plus_PM.na31.annot.csv Protocol: see manufacturer's web site
Organism:
Homo sapiens
2 DataSets
153 Series
4 Related Platforms
14616 Samples
Download data
Platform
Accession:
GPL13158
ID:
100013158
4.

Illumina HiSeq 2500 (Mus musculus)

Platform
Accession:
GPL17021
ID:
100017021
5.

Illumina HiSeq 2500 (Homo sapiens)

Platform
Accession:
GPL16791
ID:
100016791
6.

mm_rep2_cont_Input

Organism:
Mus musculus
Source name:
mouse bone marrow derived macrophages
Platform:
GPL17021
Series:
GSE61877 GSE61881
Download data
Sample
Accession:
GSM1516131
ID:
301516131
7.

mm_rep2_dex_Input

Organism:
Mus musculus
Source name:
mouse bone marrow derived macrophages
Platform:
GPL17021
Series:
GSE61877 GSE61881
Download data
Sample
Accession:
GSM1516130
ID:
301516130
8.

mm_rep2_cont_IP

Organism:
Mus musculus
Source name:
mouse bone marrow derived macrophages
Platform:
GPL17021
Series:
GSE61877 GSE61881
Download data
Sample
Accession:
GSM1516129
ID:
301516129
9.

mm_rep2_dex_IP

Organism:
Mus musculus
Source name:
mouse bone marrow derived macrophages
Platform:
GPL17021
Series:
GSE61877 GSE61881
Download data
Sample
Accession:
GSM1516128
ID:
301516128
10.

mm_rep1_cont_Input

Organism:
Mus musculus
Source name:
mouse bone marrow derived macrophages
Platform:
GPL17021
Series:
GSE61877 GSE61881
Download data
Sample
Accession:
GSM1516127
ID:
301516127
11.

mm_rep1_dex_Input

Organism:
Mus musculus
Source name:
mouse bone marrow derived macrophages
Platform:
GPL17021
Series:
GSE61877 GSE61881
Download data
Sample
Accession:
GSM1516126
ID:
301516126
12.

mm_rep1_cont_IP

Organism:
Mus musculus
Source name:
mouse bone marrow derived macrophages
Platform:
GPL17021
Series:
GSE61877 GSE61881
Download data
Sample
Accession:
GSM1516125
ID:
301516125
13.

mm_rep1_dex_IP

Organism:
Mus musculus
Source name:
mouse bone marrow derived macrophages
Platform:
GPL17021
Series:
GSE61877 GSE61881
Download data
Sample
Accession:
GSM1516124
ID:
301516124
14.

MDM-24h-dex100nM-rep4

Organism:
Homo sapiens
Source name:
monocyte derived macrophage
Platform:
GPL13158
Series:
GSE61880 GSE61881
Download data: CEL
Sample
Accession:
GSM1516175
ID:
301516175
15.

MDM-10h-dex100nM-rep4

Organism:
Homo sapiens
Source name:
monocyte derived macrophage
Platform:
GPL13158
Series:
GSE61880 GSE61881
Download data: CEL
Sample
Accession:
GSM1516174
ID:
301516174
16.

MDM-4h-dex100nM-rep4

Organism:
Homo sapiens
Source name:
monocyte derived macrophage
Platform:
GPL13158
Series:
GSE61880 GSE61881
Download data: CEL
Sample
Accession:
GSM1516173
ID:
301516173
17.

MDM-2h-dex100nM-rep4

Organism:
Homo sapiens
Source name:
monocyte derived macrophage
Platform:
GPL13158
Series:
GSE61880 GSE61881
Download data: CEL
Sample
Accession:
GSM1516172
ID:
301516172
18.

MDM-1h-dex100nM-rep4

Organism:
Homo sapiens
Source name:
monocyte derived macrophage
Platform:
GPL13158
Series:
GSE61880 GSE61881
Download data: CEL
Sample
Accession:
GSM1516171
ID:
301516171
19.

MDM-baseline-rep4

Organism:
Homo sapiens
Source name:
monocyte derived macrophage
Platform:
GPL13158
Series:
GSE61880 GSE61881
Download data: CEL
Sample
Accession:
GSM1516170
ID:
301516170
20.

MDM-24h-dex100nM-rep3

Organism:
Homo sapiens
Source name:
monocyte derived macrophage
Platform:
GPL13158
Series:
GSE61880 GSE61881
Download data: CEL
Sample
Accession:
GSM1516169
ID:
301516169
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