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Items: 4

1.

Hypoxia-induced TET-TNFa-p38-MAPK signaling axis drives tumor malignancy of human breast cancer

(Submitter supplied) Hypoxia, a hallmark of most solid tumors, leads to aberrations in epigenetic modifications promoting malignant tumor phenotypes, including metastatic features and stem cell-like characteristics. Aberrant DNA methylation has been considered to play an essential role during tumor progression and tightly associate with tumor malignancy. However, the mechanism by which hypoxia alters DNA methylation to promote tumor malignancy remains poorly understood. more...
Organism:
Homo sapiens
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL16791
2 Samples
Download data: BIGWIG
Series
Accession:
GSE60434
ID:
200060434
2.

Illumina HiSeq 2500 (Homo sapiens)

Platform
Accession:
GPL16791
ID:
100016791
3.

5hmc-MeDIP-MCF7-normoxia

Organism:
Homo sapiens
Source name:
MCF7 (human breast cancer cell line)
Platform:
GPL16791
Series:
GSE60434
Download data: BIGWIG
Sample
Accession:
GSM1479832
ID:
301479832
4.

5hmc-MeDIP-MCF7-hypoxia

Organism:
Homo sapiens
Source name:
MCF7 (human breast cancer cell line)
Platform:
GPL16791
Series:
GSE60434
Download data: BIGWIG
Sample
Accession:
GSM1479831
ID:
301479831
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Supplemental Content

db=gds|term=GSE60434[Accession]|query=1|qty=2|blobid=MCID_65e54e4355436807bfc0b621|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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