U.S. flag

An official website of the United States government

Format
Items per page
Sort by

Send to:

Choose Destination

Search results

Items: 7

1.

Global 3' RACE in yeast and humans

(Submitter supplied) Mpn1 proteins are evolutionarily conserved exonucleases that modify spliceosomal U6 small nuclear RNAs (snRNAs) post-transcriptionally. Mutations in the human MPN1 gene are associated to the genodermatosis Clericuzio-type poikiloderma with neutropenia (PN). Mpn1 deficiency leads to aberrant U6 3’ end processing and accelerated U6 decay through unknown molecular mechanisms. Here we show that in mpn1Δ fission yeast cells U6 is barely bound by the protective Lsm2-8 complex, undergoes extensive oligoadenylation and is degraded by the nuclear RNA exonuclease Rrp6 independently of the poly(A) polymerase Cid14/Trf4. more...
Organism:
Schizosaccharomyces pombe; Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL16791 GPL17225
4 Samples
Download data: TXT
Series
Accession:
GSE60197
ID:
200060197
2.

Illumina HiSeq 2500 (Schizosaccharomyces pombe)

Organism:
Schizosaccharomyces pombe
110 Series
1683 Samples
Download data
Platform
Accession:
GPL17225
ID:
100017225
3.

Illumina HiSeq 2500 (Homo sapiens)

Platform
Accession:
GPL16791
ID:
100016791
4.

mpn1Δ yeast

Organism:
Schizosaccharomyces pombe
Source name:
fission yeast
Platform:
GPL17225
Series:
GSE60197 GSE60198
Download data: TXT
Sample
Accession:
GSM1467496
ID:
301467496
5.

wt yeast

Organism:
Schizosaccharomyces pombe
Source name:
fission yeast
Platform:
GPL17225
Series:
GSE60197 GSE60198
Download data: TXT
Sample
Accession:
GSM1467495
ID:
301467495
6.

PNFF-hMPN1

Organism:
Homo sapiens
Source name:
human PN patient cells, compensated with hMPN1
Platform:
GPL16791
Series:
GSE60197 GSE60198
Download data: TXT
Sample
Accession:
GSM1467498
ID:
301467498
7.

PNFF-ev

Organism:
Homo sapiens
Source name:
human PN patient cells
Platform:
GPL16791
Series:
GSE60197 GSE60198
Download data: TXT
Sample
Accession:
GSM1467497
ID:
301467497
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=GSE60197[Accession]|query=1|qty=3|blobid=MCID_67b211e81a48797f60688b1d|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Search details

See more...

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center