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Items: 1 to 20 of 42

1.

Uridylation by TUT4 and TUT7 marks mRNA for degradation [TAIL-Seq]

(Submitter supplied) Uridylation occurs pervasively on mRNAs in mammals, yet its mechanism and significance remain unknown. Here we identify TUT4 and TUT7 (also known as ZCCHC11 and ZCCHC6, respectively) as the enzymes that uridylate mRNAs. Uridylation readily occurs on deadenylated mRNAs that are not associated with poly(A) binding protein (PABPC1) in cells. Consistently, purified TUT4 and TUT7 (TUT4/7) selectively uridylate RNAs with short A tails (< ~25 nt) while PABPC1 antagonizes uridylation of polyadenylated mRNAs in vitro. more...
Organism:
Homo sapiens
Type:
Other
Platforms:
GPL15520 GPL16791
39 Samples
Download data: TXT
Series
Accession:
GSE59627
ID:
200059627
2.

Illumina HiSeq 2500 (Homo sapiens)

Platform
Accession:
GPL16791
ID:
100016791
3.

Illumina MiSeq (Homo sapiens)

Platform
Accession:
GPL15520
ID:
100015520
4.

TAIL-seq exp #9 siTUT47

Organism:
Homo sapiens
Source name:
TS9_siTUT47
Platform:
GPL16791
Series:
GSE59627
Download data: TXT
Sample
Accession:
GSM1514017
ID:
301514017
5.

TAIL-seq exp #9 siCont

Organism:
Homo sapiens
Source name:
TS9_siCont
Platform:
GPL16791
Series:
GSE59627
Download data: TXT
Sample
Accession:
GSM1514016
ID:
301514016
6.

TAIL-seq exp #8 Nucleus

Organism:
Homo sapiens
Source name:
TS8_Nuc
Platform:
GPL16791
Series:
GSE59627 GSE59628
Download data: TXT
Sample
Accession:
GSM1440684
ID:
301440684
7.

TAIL-seq exp #8 Cytoplasm

Organism:
Homo sapiens
Source name:
TS8_Cyto
Platform:
GPL16791
Series:
GSE59627 GSE59628
Download data: TXT
Sample
Accession:
GSM1440683
ID:
301440683
8.

TAIL-seq exp #3 siTUT47

Organism:
Homo sapiens
Source name:
TS3_siTUT47
Platform:
GPL16791
Series:
GSE59627 GSE59628
Download data: TXT
Sample
Accession:
GSM1440671
ID:
301440671
9.

TAIL-seq exp #3 siCont

Organism:
Homo sapiens
Source name:
TS3_siCont
Platform:
GPL16791
Series:
GSE59627 GSE59628
Download data: TXT
Sample
Accession:
GSM1440670
ID:
301440670
10.

TAIL-seq exp #13 siTUT247

Organism:
Homo sapiens
Source name:
TS13_siTUT247
Platform:
GPL15520
Series:
GSE59627
Download data: TXT
Sample
Accession:
GSM1514032
ID:
301514032
11.

TAIL-seq exp #13 siTUT1356

Organism:
Homo sapiens
Source name:
TS13_siTUT1356
Platform:
GPL15520
Series:
GSE59627
Download data: TXT
Sample
Accession:
GSM1514031
ID:
301514031
12.

TAIL-seq exp #13 siLuc

Organism:
Homo sapiens
Source name:
TS13_siLuc
Platform:
GPL15520
Series:
GSE59627
Download data: TXT
Sample
Accession:
GSM1514030
ID:
301514030
13.

TAIL-seq exp #12 TUT7 Knockcout

Organism:
Homo sapiens
Source name:
TS12_T7KO
Platform:
GPL15520
Series:
GSE59627
Download data: TXT
Sample
Accession:
GSM1514029
ID:
301514029
14.

TAIL-seq exp #12 TUT4 Knockout

Organism:
Homo sapiens
Source name:
TS12_T4KO
Platform:
GPL15520
Series:
GSE59627
Download data: TXT
Sample
Accession:
GSM1514028
ID:
301514028
15.

TAIL-seq exp #12 TUT2 Knockout

Organism:
Homo sapiens
Source name:
TS12_T2KO
Platform:
GPL15520
Series:
GSE59627
Download data: TXT
Sample
Accession:
GSM1514027
ID:
301514027
16.

TAIL-seq exp #12 Mock

Organism:
Homo sapiens
Source name:
TS12_Mock
Platform:
GPL15520
Series:
GSE59627
Download data: TXT
Sample
Accession:
GSM1514026
ID:
301514026
17.

TAIL-seq exp #11 siTUT47 (siRNA set #1 and #2)

Organism:
Homo sapiens
Source name:
TS11_siTUT47mix
Platform:
GPL15520
Series:
GSE59627
Download data: TXT
Sample
Accession:
GSM1514025
ID:
301514025
18.

TAIL-seq exp #11 siTUT47 (siRNA set #2)

Organism:
Homo sapiens
Source name:
TS11_siTUT47b
Platform:
GPL15520
Series:
GSE59627
Download data: TXT
Sample
Accession:
GSM1514024
ID:
301514024
19.

TAIL-seq exp #11 siTUT47 (siRNA set #1)

Organism:
Homo sapiens
Source name:
TS11_siTUT47a
Platform:
GPL15520
Series:
GSE59627
Download data: TXT
Sample
Accession:
GSM1514023
ID:
301514023
20.

TAIL-seq exp #11 siCont

Organism:
Homo sapiens
Source name:
TS11_siCont
Platform:
GPL15520
Series:
GSE59627
Download data: TXT
Sample
Accession:
GSM1514022
ID:
301514022
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Supplemental Content

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