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Items: 6

1.

Extensive remodeling of DC function by rapid maturation-induced epigenetic gene silencing

(Submitter supplied) Dendritic-cell (DC) maturation involves substantial remodeling of their gene-expression program. Most research has focused on inducible gene-expression networks promoting the acquisition of new functions, such as cytokine production and enhanced T-cell-stimulatory capacity. In contrast, mechanisms that modulate DC-function by inducing gene silencing remain poorly understood. Here we describe a novel primary epigenetic-silencing response that makes major contributions to the DC-maturation process. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL16791
4 Samples
Download data: BED, BW
Series
Accession:
GSE58864
ID:
200058864
2.

Illumina HiSeq 2500 (Homo sapiens)

Platform
Accession:
GPL16791
ID:
100016791
3.

Pu.1_ChIPseq rep2

Organism:
Homo sapiens
Source name:
Dendritic cells
Platform:
GPL16791
Series:
GSE58864
Download data: BED, BW
Sample
Accession:
GSM1421019
ID:
301421019
4.

Input DNA rep2

Organism:
Homo sapiens
Source name:
Dendritic cells
Platform:
GPL16791
Series:
GSE58864
Download data: BW
Sample
Accession:
GSM1421018
ID:
301421018
5.

Pu.1_ChIPseq rep1

Organism:
Homo sapiens
Source name:
Dendritic cells
Platform:
GPL16791
Series:
GSE58864
Download data: BED, BW
Sample
Accession:
GSM1421017
ID:
301421017
6.

Input DNA rep1

Organism:
Homo sapiens
Source name:
Dendritic cells
Platform:
GPL16791
Series:
GSE58864
Download data: BW
Sample
Accession:
GSM1421016
ID:
301421016
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Supplemental Content

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