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Items: 1 to 20 of 58

1.

Opposing roles for the lncRNA Haunt and its genomic locus in regulating HOXA gene activation during embryonic stem cell differentiation

(Submitter supplied) Long noncoding RNAs (lncRNAs) have been implicated in controlling various aspects of embryonic stem cell (ESC) biology, although the functions of specific lncRNAs, and the molecular mechanisms through which they act, remain unclear. Here, we demonstrate discrete and opposing roles for the lncRNA transcript Haunt and its genomic locus in regulating the HOXA gene cluster during ESC differentiation. Reducing or enhancing Haunt expression, with minimal disruption of the Haunt locus, led to up- or down-regulation of HOXA genes, respectively. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL17021 GPL18480 GPL13112
54 Samples
Download data: BEDGRAPH, BIGWIG, TXT, XLSX
Series
Accession:
GSE58514
ID:
200058514
2.

Illumina HiSeq 1500 (Mus musculus)

Platform
Accession:
GPL18480
ID:
100018480
3.

Illumina HiSeq 2500 (Mus musculus)

Platform
Accession:
GPL17021
ID:
100017021
4.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
5.

HOXA-b_D4

Organism:
Mus musculus
Source name:
HOXA KO mES cells
Platform:
GPL13112
Series:
GSE58514
Download data
Sample
Accession:
GSM1604254
ID:
301604254
6.

HOXA-a_D4

Organism:
Mus musculus
Source name:
HOXA KO mES cells
Platform:
GPL13112
Series:
GSE58514
Download data
Sample
Accession:
GSM1604253
ID:
301604253
7.

CAG KI-b_D4

Organism:
Mus musculus
Source name:
Haunt CAG KI mES cells
Platform:
GPL13112
Series:
GSE58514
Download data
Sample
Accession:
GSM1604252
ID:
301604252
8.

CAG KI-a_D4

Organism:
Mus musculus
Source name:
Haunt CAG KI mES cells
Platform:
GPL13112
Series:
GSE58514
Download data
Sample
Accession:
GSM1604251
ID:
301604251
9.

58 kb KO-b_D4

Organism:
Mus musculus
Source name:
Haunt 58 kb KO mES cells
Platform:
GPL13112
Series:
GSE58514
Download data
Sample
Accession:
GSM1604250
ID:
301604250
10.

58 kb KO-a_D4

Organism:
Mus musculus
Source name:
Haunt 58 kb KO mES cells
Platform:
GPL13112
Series:
GSE58514
Download data
Sample
Accession:
GSM1604249
ID:
301604249
11.

pKO-b_D4

Organism:
Mus musculus
Source name:
Haunt pKO mES cells
Platform:
GPL13112
Series:
GSE58514
Download data
Sample
Accession:
GSM1604248
ID:
301604248
12.

pKO-a_D4

Organism:
Mus musculus
Source name:
Haunt pKO mES cells
Platform:
GPL13112
Series:
GSE58514
Download data
Sample
Accession:
GSM1604247
ID:
301604247
13.

WT-2_D4

Organism:
Mus musculus
Source name:
46C mES cells
Platform:
GPL13112
Series:
GSE58514
Download data
Sample
Accession:
GSM1604246
ID:
301604246
14.

WT-1_D4

Organism:
Mus musculus
Source name:
46C mES cells (pKO control)
Platform:
GPL13112
Series:
GSE58514
Download data
Sample
Accession:
GSM1604245
ID:
301604245
15.

HOXA-b_D2

Organism:
Mus musculus
Source name:
HOXA KO mES cells
Platform:
GPL13112
Series:
GSE58514
Download data
Sample
Accession:
GSM1604244
ID:
301604244
16.

HOXA-a_D2

Organism:
Mus musculus
Source name:
HOXA KO mES cells
Platform:
GPL13112
Series:
GSE58514
Download data
Sample
Accession:
GSM1604243
ID:
301604243
17.

CAG KI-b_D2

Organism:
Mus musculus
Source name:
Haunt CAG KI mES cells
Platform:
GPL13112
Series:
GSE58514
Download data
Sample
Accession:
GSM1604242
ID:
301604242
18.

CAG KI-a_D2

Organism:
Mus musculus
Source name:
Haunt CAG KI mES cells
Platform:
GPL13112
Series:
GSE58514
Download data
Sample
Accession:
GSM1604241
ID:
301604241
19.

58 kb KO-b_D2

Organism:
Mus musculus
Source name:
Haunt 58 kb KO mES cells
Platform:
GPL13112
Series:
GSE58514
Download data
Sample
Accession:
GSM1604240
ID:
301604240
20.

58 kb KO-a_D2

Organism:
Mus musculus
Source name:
Haunt 58 kb KO mES cells
Platform:
GPL13112
Series:
GSE58514
Download data
Sample
Accession:
GSM1604239
ID:
301604239
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Supplemental Content

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