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Items: 1 to 20 of 44

1.

RNA-seq analysis of vorinostat-resistant HCT116 cells following gene knockdown of GLI1 or PSMD13 with or without vorinostat treatment

(Submitter supplied) Transcriptome analysis was conducted on vorinostat resistant HCT116 cells (HCT116-VR) upon knockdown of potential vorinostat resistance candidate genes in the presence and absence of vorinostat. Potential vorinostat resistance candidate genes chosen for this study were GLI1 and PSMD13, which were identified through a genome-wide synthetic lethal RNA interference screen. To understand the transcriptional events underpinning the effect of GLI1 and PSMD13 knockdown (sensitisation to vorinostat-induced apoptosis), cells were first subjected to gene knockdown, then to treatment with vorinsotat or the solvent control. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16791
42 Samples
Download data: TSV
2.

Illumina HiSeq 2500 (Homo sapiens)

Platform
Accession:
GPL16791
ID:
100016791
3.

siPSMD13_vorinostat_12hr rep3

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL16791
Series:
GSE57871
Download data
Sample
Accession:
GSM1395398
ID:
301395398
4.

siPSMD13_vorinostat_8hr rep3

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL16791
Series:
GSE57871
Download data
Sample
Accession:
GSM1395397
ID:
301395397
5.

siPSDM13_DMSO_12hr rep3

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL16791
Series:
GSE57871
Download data
Sample
Accession:
GSM1395396
ID:
301395396
6.

siPSMD13_DMSO_8hr rep3

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL16791
Series:
GSE57871
Download data
Sample
Accession:
GSM1395395
ID:
301395395
7.

siGLI1_vorinostat_8hr rep3

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL16791
Series:
GSE57871
Download data
Sample
Accession:
GSM1395394
ID:
301395394
8.

siGLI1_vorinostat_4hr rep3

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL16791
Series:
GSE57871
Download data
Sample
Accession:
GSM1395393
ID:
301395393
9.

siGLI1_DMSO_8hr rep3

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL16791
Series:
GSE57871
Download data
Sample
Accession:
GSM1395392
ID:
301395392
10.

siGLI1_DMSO_4hr rep3

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL16791
Series:
GSE57871
Download data
Sample
Accession:
GSM1395391
ID:
301395391
11.

mock_vorinostat_12hr rep3

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL16791
Series:
GSE57871
Download data
Sample
Accession:
GSM1395390
ID:
301395390
12.

mock_vorinostat_8hr rep3

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL16791
Series:
GSE57871
Download data
Sample
Accession:
GSM1395389
ID:
301395389
13.

mock_vorinostat_4hr rep3

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL16791
Series:
GSE57871
Download data
Sample
Accession:
GSM1395388
ID:
301395388
14.

mock_DMSO_12hr rep3

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL16791
Series:
GSE57871
Download data
Sample
Accession:
GSM1395387
ID:
301395387
15.

mock_DMSO_8hr rep3

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL16791
Series:
GSE57871
Download data
Sample
Accession:
GSM1395386
ID:
301395386
16.

mock_DMSO_4hr rep3

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL16791
Series:
GSE57871
Download data
Sample
Accession:
GSM1395385
ID:
301395385
17.

siPSMD13_vorinostat_12hr rep2

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL16791
Series:
GSE57871
Download data
Sample
Accession:
GSM1395384
ID:
301395384
18.

siPSMD13_vorinostat_8hr rep2

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL16791
Series:
GSE57871
Download data
Sample
Accession:
GSM1395383
ID:
301395383
19.

siPSDM13_DMSO_12hr rep2

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL16791
Series:
GSE57871
Download data
Sample
Accession:
GSM1395382
ID:
301395382
20.

siPSMD13_DMSO_8hr rep2

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL16791
Series:
GSE57871
Download data
Sample
Accession:
GSM1395381
ID:
301395381
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