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Items: 17

1.

Aplidin synergizes with cytosine arabinoside: functional relevance of mitochondria in Aplidin-induced cytotoxicity

(Submitter supplied) Aplidin (plitidepsin) is a novel marine-derived antitumor agent presently undergoing phase II clinical trials in hematological malignancies and solid tumors. Lack of bone marrow toxicity has encouraged further development of this drug for treatment of leukemia and lymphoma. Multiple signaling pathways have been shown to be involved in Aplidin-induced apoptosis and cell cycle arrest in G1 and G2 phase. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS2295
Platform:
GPL571
14 Samples
Download data: CEL
Series
Accession:
GSE5681
ID:
200005681
2.
Full record GDS2295

Aplidin and cytarabine effect on diffuse large B cell lymphoma cell line

Analysis of diffuse large B cell lymphoma SKI-DLCL cells treated with Aplidin, cytarabine (AraC), or both anticancer drugs. The effect of the drugs on animals with SKI-DLCL cell-derived tumors also examined. Results provide insight into the action of Aplidin alone and in combination with AraC.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 4 agent, 2 protocol sets
Platform:
GPL571
Series:
GSE5681
14 Samples
Download data: CEL
DataSet
Accession:
GDS2295
ID:
2295
3.

[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Human Genome U133A 2.0 Array is a single array representing 14,500 well-characterized human genes that can be used to explore human biology and disease processes. more...
Organism:
Homo sapiens
84 DataSets
638 Series
12 Related Platforms
24352 Samples
Download data
Platform
Accession:
GPL571
ID:
100000571
4.

SKI-DLCL cells_Aplidin 1.5 nM AraC 5.0 nM_24h_rpt3

Organism:
Homo sapiens
Source name:
SKI-DLCL cells
Platform:
GPL571
Series:
GSE5681
Dataset:
GDS2295
Download data: CEL
Sample
Accession:
GSM132960
ID:
300132960
5.

SKI-DLCL cells_Aplidin 1.5 nM AraC 5nM_24h_rpt2

Organism:
Homo sapiens
Source name:
SKI-DLCL cells
Platform:
GPL571
Series:
GSE5681
Dataset:
GDS2295
Download data: CEL
Sample
Accession:
GSM132956
ID:
300132956
6.

SKI-DLCL cells_Aplidin 1.5nM AraC 5nM_24h_rpt1

Organism:
Homo sapiens
Source name:
SKI-DLCL cells
Platform:
GPL571
Series:
GSE5681
Dataset:
GDS2295
Download data: CEL
Sample
Accession:
GSM132955
ID:
300132955
7.

SKI-DLCL cells_AraC 20nM_24h_rpt3

Organism:
Homo sapiens
Source name:
SKI-DLCL cells
Platform:
GPL571
Series:
GSE5681
Dataset:
GDS2295
Download data: CEL
Sample
Accession:
GSM132953
ID:
300132953
8.

SKI-DLCL cells_AraC 20nM_24h_rpt2

Organism:
Homo sapiens
Source name:
SKI-DLCL cells
Platform:
GPL571
Series:
GSE5681
Dataset:
GDS2295
Download data: CEL
Sample
Accession:
GSM132950
ID:
300132950
9.

SKI-DLCL cells_AraC 20nM_24h_rpt1

Organism:
Homo sapiens
Source name:
SKI-DLCL cells
Platform:
GPL571
Series:
GSE5681
Dataset:
GDS2295
Download data: CEL
Sample
Accession:
GSM132949
ID:
300132949
10.

SKI-DLCL cells_Aplidin treated 3nM_24h_rpt3

Organism:
Homo sapiens
Source name:
SKI-DLCL cells
Platform:
GPL571
Series:
GSE5681
Dataset:
GDS2295
Download data: CEL
Sample
Accession:
GSM132947
ID:
300132947
11.

SKI-DLCL cells_Aplidin 3.0nM_24h_rpt2

Organism:
Homo sapiens
Source name:
SKI-DLCL cells
Platform:
GPL571
Series:
GSE5681
Dataset:
GDS2295
Download data: CEL
Sample
Accession:
GSM132944
ID:
300132944
12.

SKI-DLCL cells_Aplidin 3nM_24h_rpt1

Organism:
Homo sapiens
Source name:
SKI-DLCL cells
Platform:
GPL571
Series:
GSE5681
Dataset:
GDS2295
Download data: CEL
Sample
Accession:
GSM132941
ID:
300132941
13.

SKI-DLCL cells_untreated_24h_rpt3

Organism:
Homo sapiens
Source name:
SKI-DLCL cells
Platform:
GPL571
Series:
GSE5681
Dataset:
GDS2295
Download data: CEL
Sample
Accession:
GSM132920
ID:
300132920
14.

SKI-DLCL cells_untreated_24h_2rpt

Organism:
Homo sapiens
Source name:
SKI-DLCL cells
Platform:
GPL571
Series:
GSE5681
Dataset:
GDS2295
Download data: CEL
Sample
Accession:
GSM132918
ID:
300132918
15.

SKI-DLCL cells_untreated_24h_1rpt

Organism:
Homo sapiens
Source name:
SKI-DLCL cells untreated
Platform:
GPL571
Series:
GSE5681
Dataset:
GDS2295
Download data: CEL
Sample
Accession:
GSM132917
ID:
300132917
16.

SKI-DLCL_tumor_animals treated with 1mg/kg Aplidin_50mg/kg AraC

Organism:
Homo sapiens
Source name:
RNA isolated from SKI-DLCL tumor harvested from mice treated with Aplidin and AraC
Platform:
GPL571
Series:
GSE5681
Dataset:
GDS2295
Download data: CEL
Sample
Accession:
GSM132916
ID:
300132916
17.

SKI-DLCL_tumor_untreated animals

Organism:
Homo sapiens
Source name:
SKI-DLCL tumor in CB-17 scid/scid mice, untreated, control
Platform:
GPL571
Series:
GSE5681
Dataset:
GDS2295
Download data: CEL
Sample
Accession:
GSM132760
ID:
300132760
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