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Items: 1 to 20 of 51

1.

Stage-specific control of early B cell development by the transcription factor Ikaros

(Submitter supplied) Ikaros is an essential regulator of lymphopoiesis. Here, we studied the B-cell-specific function of Ikaros by conditional Ikzf1 inactivation in pro-B cells. B-cell development was arrested at an aberrant ‘pro-B’ cell stage characterized by increased cell adhesion and loss of pre-B cell receptor signaling. Ikaros was found to activate genes coding for pre-BCR signal transducers and to repress genes involved in the downregulation of pre-BCR signaling and upregulation of the integrin signaling pathway. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL13112 GPL11002
48 Samples
Download data: BW, TXT
Series
Accession:
GSE53595
ID:
200053595
2.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
3.

Illumina Genome Analyzer IIx (Mus musculus)

Platform
Accession:
GPL11002
ID:
100011002
4.

H3K4me3 ChIP–seq Rag2(–/–) Ikzf1(∆/–) pro-B 15842

Organism:
Mus musculus
Source name:
Pro-B cell
Platform:
GPL13112
Series:
GSE53595
Download data: BW
Sample
Accession:
GSM1296579
ID:
301296579
5.

H3K4me3 ChIP–seq Rag2(–/–) Ikzf1(∆/–) pro-B 15841

Organism:
Mus musculus
Source name:
Pro-B cell
Platform:
GPL13112
Series:
GSE53595
Download data: BW
Sample
Accession:
GSM1296578
ID:
301296578
6.

H3K4me3 ChIP–seq Rag2(–/–) Ikzf1(∆/+) pro-B 15840

Organism:
Mus musculus
Source name:
Pro-B cell
Platform:
GPL13112
Series:
GSE53595
Download data: BW
Sample
Accession:
GSM1296577
ID:
301296577
7.

H3K4me3 ChIP–seq Rag2(–/–) Ikzf1(∆/+) pro-B 15839

Organism:
Mus musculus
Source name:
Pro-B cell
Platform:
GPL13112
Series:
GSE53595
Download data: BW
Sample
Accession:
GSM1296576
ID:
301296576
8.

H3K9ac ChIP–seq Rag2(–/–) Ikzf1(∆/–) pro-B 15834

Organism:
Mus musculus
Source name:
Pro-B cell
Platform:
GPL13112
Series:
GSE53595
Download data: BW
Sample
Accession:
GSM1296575
ID:
301296575
9.

H3K9ac ChIP–seq Rag2(–/–) Ikzf1(∆/–) pro-B 15833

Organism:
Mus musculus
Source name:
Pro-B cell
Platform:
GPL13112
Series:
GSE53595
Download data: BW
Sample
Accession:
GSM1296574
ID:
301296574
10.

H3K9ac ChIP–seq Rag2(–/–) Ikzf1(∆/+) pro-B 15832

Organism:
Mus musculus
Source name:
Pro-B cell
Platform:
GPL13112
Series:
GSE53595
Download data: BW
Sample
Accession:
GSM1296573
ID:
301296573
11.

H3K9ac ChIP–seq Rag2(–/–) Ikzf1(∆/+) pro-B 15831

Organism:
Mus musculus
Source name:
Pro-B cell
Platform:
GPL13112
Series:
GSE53595
Download data: BW
Sample
Accession:
GSM1296572
ID:
301296572
12.

RNA-seq Ikaros KD Ik2709 pre-pro-B 15291

Organism:
Mus musculus
Source name:
Pre-pro-B cell
Platform:
GPL13112
Series:
GSE53595
Download data: TXT
Sample
Accession:
GSM1296571
ID:
301296571
13.

RNA-seq Ikaros KD Ik4056 pre-pro-B 15290

Organism:
Mus musculus
Source name:
Pre-pro-B cell
Platform:
GPL13112
Series:
GSE53595
Download data: TXT
Sample
Accession:
GSM1296570
ID:
301296570
14.

RNA-seq Ikaros KD Ren713 control pre-pro-B 15289

Organism:
Mus musculus
Source name:
Pre-pro-B cell
Platform:
GPL13112
Series:
GSE53595
Download data: TXT
Sample
Accession:
GSM1296569
ID:
301296569
15.

RNA-seq Ikaros KD empty vector control pre-pro-B 15288

Organism:
Mus musculus
Source name:
Pre-pro-B cell
Platform:
GPL13112
Series:
GSE53595
Download data: TXT
Sample
Accession:
GSM1296568
ID:
301296568
16.

RNA-seq Ikaros KD Ik2709 pre-pro-B 15285

Organism:
Mus musculus
Source name:
Pre-pro-B cell
Platform:
GPL13112
Series:
GSE53595
Download data: TXT
Sample
Accession:
GSM1296567
ID:
301296567
17.

RNA-seq Ikaros KD Ik4056 pre-pro-B 15284

Organism:
Mus musculus
Source name:
Pre-pro-B cell
Platform:
GPL13112
Series:
GSE53595
Download data: TXT
Sample
Accession:
GSM1296566
ID:
301296566
18.

RNA-seq Ikaros KD Ren713 control pre-pro-B 15283

Organism:
Mus musculus
Source name:
Pre-pro-B cell
Platform:
GPL13112
Series:
GSE53595
Download data: TXT
Sample
Accession:
GSM1296565
ID:
301296565
19.

RNA-seq Ikaros KD empty vector control pre-pro-B 15282

Organism:
Mus musculus
Source name:
Pre-pro-B cell
Platform:
GPL13112
Series:
GSE53595
Download data: TXT
Sample
Accession:
GSM1296564
ID:
301296564
20.

RNA-seq Ikaros KD Ik2709 pre-pro-B 15279

Organism:
Mus musculus
Source name:
Pre-pro-B cell
Platform:
GPL13112
Series:
GSE53595
Download data: TXT
Sample
Accession:
GSM1296563
ID:
301296563
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Supplemental Content

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