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Items: 1 to 20 of 27

1.

Targeting H3K4 methylation as a therapeutic strategy for Huntington's disease (RNA-seq)

(Submitter supplied) Transcriptional dysregulation is an early feature of Huntington's disease (HD). We observed gene-specific changes in H3K4me3 at transcriptionally repressed promoters in R6/2 mouse and human HD brain. Genome-wide analysis showed a novel chromatin signature for this mark. Reducing the levels of the H3K4 demethylase SMCX/Jarid1c in primary neurons reversed down-regulation of key neuronal genes caused by mutant Huntingtin (Htt) expression. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL13112 GPL11002
24 Samples
Download data: RPKM, TXT
Series
Accession:
GSE48962
ID:
200048962
2.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
3.

Illumina Genome Analyzer IIx (Mus musculus)

Platform
Accession:
GPL11002
ID:
100011002
4.

TSW491

Organism:
Mus musculus
Source name:
R6/2 wildtype littermate, striatum, 12 weeks
Platform:
GPL11002
Series:
GSE48962 GSE48963
Download data: RPKM
Sample
Accession:
GSM1187672
ID:
301187672
5.

TSW479

Organism:
Mus musculus
Source name:
R6/2 wildtype littermate, striatum, 12 weeks
Platform:
GPL11002
Series:
GSE48962 GSE48963
Download data: RPKM
Sample
Accession:
GSM1187671
ID:
301187671
6.

TSW478

Organism:
Mus musculus
Source name:
R6/2 wildtype littermate, striatum, 12 weeks
Platform:
GPL11002
Series:
GSE48962 GSE48963
Download data: RPKM
Sample
Accession:
GSM1187670
ID:
301187670
7.

TSM490

Organism:
Mus musculus
Source name:
R6/2, striatum, 12 weeks
Platform:
GPL11002
Series:
GSE48962 GSE48963
Download data: RPKM
Sample
Accession:
GSM1187668
ID:
301187668
8.

TSM482

Organism:
Mus musculus
Source name:
R6/2, striatum, 12 weeks
Platform:
GPL11002
Series:
GSE48962 GSE48963
Download data: RPKM
Sample
Accession:
GSM1187667
ID:
301187667
9.

TCW9469

Organism:
Mus musculus
Source name:
R6/2 wildtype littermate, cortex, 12 weeks
Platform:
GPL11002
Series:
GSE48962 GSE48963
Download data: RPKM
Sample
Accession:
GSM1187666
ID:
301187666
10.

TCW9457

Organism:
Mus musculus
Source name:
R6/2 wildtype littermate, cortex, 12 weeks
Platform:
GPL11002
Series:
GSE48962 GSE48963
Download data: RPKM
Sample
Accession:
GSM1187665
ID:
301187665
11.

TCW9451

Organism:
Mus musculus
Source name:
R6/2 wildtype littermate, cortex, 12 weeks
Platform:
GPL11002
Series:
GSE48962 GSE48963
Download data: RPKM
Sample
Accession:
GSM1187664
ID:
301187664
12.

TCM9453

Organism:
Mus musculus
Source name:
R6/2, cortex, 12 weeks
Platform:
GPL11002
Series:
GSE48962 GSE48963
Download data: RPKM
Sample
Accession:
GSM1187663
ID:
301187663
13.

TCM9450

Organism:
Mus musculus
Source name:
R6/2, cortex, 12 weeks
Platform:
GPL11002
Series:
GSE48962 GSE48963
Download data: RPKM
Sample
Accession:
GSM1187661
ID:
301187661
14.

ESW183

Organism:
Mus musculus
Source name:
R6/2 wildtype littermate, striatum, 8 weeks
Platform:
GPL11002
Series:
GSE48962 GSE48963
Download data: RPKM
Sample
Accession:
GSM1187660
ID:
301187660
15.

ESW180

Organism:
Mus musculus
Source name:
R6/2 wildtype littermate, striatum, 8 weeks
Platform:
GPL11002
Series:
GSE48962 GSE48963
Download data: RPKM
Sample
Accession:
GSM1187659
ID:
301187659
16.

ESW176

Organism:
Mus musculus
Source name:
R6/2 wildtype littermate, striatum, 8 weeks
Platform:
GPL11002
Series:
GSE48962 GSE48963
Download data: RPKM
Sample
Accession:
GSM1187658
ID:
301187658
17.

ESM192

Organism:
Mus musculus
Source name:
R6/2, striatum, 8 weeks
Platform:
GPL11002
Series:
GSE48962 GSE48963
Download data: RPKM
Sample
Accession:
GSM1187657
ID:
301187657
18.

ESM184

Organism:
Mus musculus
Source name:
R6/2, striatum, 8 weeks
Platform:
GPL11002
Series:
GSE48962 GSE48963
Download data: RPKM
Sample
Accession:
GSM1187656
ID:
301187656
19.

ESM181

Organism:
Mus musculus
Source name:
R6/2, striatum, 8 weeks
Platform:
GPL11002
Series:
GSE48962 GSE48963
Download data: RPKM
Sample
Accession:
GSM1187655
ID:
301187655
20.

ECW180

Organism:
Mus musculus
Source name:
R6/2 wildtype littermate, cortex, 8 weeks
Platform:
GPL11002
Series:
GSE48962 GSE48963
Download data: RPKM
Sample
Accession:
GSM1187654
ID:
301187654
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Supplemental Content

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