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Items: 9

1.

Maintenance of DNA methylation in embryonic stem cells depends on the histone H3K9 methyltransferases (Dnmt3ab KO Methyl-Seq)

(Submitter supplied) During mammalian development DNA methylation patterns need to be reset in primordial germ cells (PGC) and preimplantation embryos. However, many retro-transposons and imprinted genes are resistant to such global epigenetic reprogramming via hitherto undefined mechanisms. Here, we report that some of these sequences are immune to widespread erasure of DNA methylation in the mouse embryonic stem cells (mESCs) lacking de novo DNA methyltransferases. more...
Organism:
Mus musculus
Type:
Methylation profiling by high throughput sequencing
Platforms:
GPL13112 GPL11002
6 Samples
Download data: BW
Series
Accession:
GSE47893
ID:
200047893
2.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
3.

Illumina Genome Analyzer IIx (Mus musculus)

Platform
Accession:
GPL11002
ID:
100011002
4.

methyl-C-seq_DKO_rep paired end

Organism:
Mus musculus
Source name:
mouse embryonic stem cells
Platform:
GPL13112
Series:
GSE47893 GSE47894
Download data
Sample
Accession:
GSM1162048
ID:
301162048
5.

methyl-C-seq_DKO_rep2

Organism:
Mus musculus
Source name:
mouse embryonic stem cells
Platform:
GPL13112
Series:
GSE47893 GSE47894
Download data: BW
Sample
Accession:
GSM1162047
ID:
301162047
6.

methyl-C-seq_WT_rep2 paired end

Organism:
Mus musculus
Source name:
mouse embryonic stem cells
Platform:
GPL13112
Series:
GSE47893 GSE47894
Download data
Sample
Accession:
GSM1162045
ID:
301162045
7.

methyl-C-seq_WT_rep2

Organism:
Mus musculus
Source name:
mouse embryonic stem cells
Platform:
GPL13112
Series:
GSE47893 GSE47894
Download data: BW
Sample
Accession:
GSM1162044
ID:
301162044
8.

methyl-C-seq_DKO_rep1

Organism:
Mus musculus
Source name:
mouse embryonic stem cells
Platform:
GPL11002
Series:
GSE47893 GSE47894
Download data: BW
Sample
Accession:
GSM1162046
ID:
301162046
9.

methyl-C-seq_WT_rep1

Organism:
Mus musculus
Source name:
mouse embryonic stem cells
Platform:
GPL11002
Series:
GSE47893 GSE47894
Download data: BW
Sample
Accession:
GSM1162043
ID:
301162043
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Supplemental Content

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