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Items: 6

1.

Let-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts [mRNA-seq_Flag-HA-NR6A1_overexpr]

(Submitter supplied) MicroRNAs (miRNAs) are critical to proliferation, differentiation, and development. Here, we characterize gene expression in murine Dicer-null adult mesenchymal stem cell lines, a fibroblast cell type. Loss of Dicer leads to de-repression of let-7 targets at levels that exceed 10-100 fold with increases in transcription. Direct and indirect targets of this miRNA belong to a mid-gestation embryonic program that encompasses known oncofetal genes as well as oncogenes not previously associated with an embryonic state. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13112
4 Samples
Download data: TXT
Series
Accession:
GSE44158
ID:
200044158
2.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
3.

Flag-HA-NR6A1_Clone12

Organism:
Mus musculus
Source name:
Dicer f/f murine MSC cell line
Platform:
GPL13112
Series:
GSE44158 GSE44163
Download data
Sample
Accession:
GSM1079800
ID:
301079800
4.

Flag-HA-NR6A1_Clone6

Organism:
Mus musculus
Source name:
Dicer f/f murine MSC cell line
Platform:
GPL13112
Series:
GSE44158 GSE44163
Download data
Sample
Accession:
GSM1079799
ID:
301079799
5.

Vector_Clone12

Organism:
Mus musculus
Source name:
Dicer f/f murine MSC cell line
Platform:
GPL13112
Series:
GSE44158 GSE44163
Download data
Sample
Accession:
GSM1079798
ID:
301079798
6.

Vector_Clone6

Organism:
Mus musculus
Source name:
Dicer f/f murine MSC cell line
Platform:
GPL13112
Series:
GSE44158 GSE44163
Download data
Sample
Accession:
GSM1079797
ID:
301079797
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Supplemental Content

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