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Items: 4

1.

High-resolution enzymatic mapping of genomic 5-hydroxymethylcytosine in mouse embryonic stem cells

(Submitter supplied) We describe the use of a novel DNA modification-dependent restriction endonuclease AbaSI coupled with sequencing (Aba-seq) to map high-resolution hydroxymethylome of mouse E14 embryonic stem cells. The specificity of AbaSI enables sensitive detection of 5hmC at low occupancy regions. Bioinformatic analysis suggests 5hmCs in genic regions closely follows the 5mC distribution. 5hmC is generally depleted in CpG islands and only enriched in a small set of repetitive elements. more...
Organism:
Mus musculus
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL13112
2 Samples
Download data: TXT
Series
Accession:
GSE42898
ID:
200042898
2.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
3.

E14_AbaSeq_rep2

Organism:
Mus musculus
Source name:
embryonic stem cell (E14)
Platform:
GPL13112
Series:
GSE42898
Download data
Sample
Accession:
GSM1053064
ID:
301053064
4.

E14_AbaSeq_rep1

Organism:
Mus musculus
Source name:
embryonic stem cell (E14)
Platform:
GPL13112
Series:
GSE42898
Download data
Sample
Accession:
GSM1053063
ID:
301053063
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Supplemental Content

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