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Items: 1 to 20 of 33

1.

Genome-wide profiling of 5-Formylcytosine reveals it roles in epigenetic priming

(Submitter supplied) TET proteins oxidize 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC). 5fC and 5caC are excised by mammalian DNA glycosylase TDG, implicating 5mC oxidation in DNA demethylation. Here we show that the genomic locations of 5fC can be determined by coupling chemical reduction with biotin tagging. Genome-wide mapping of 5fC in mouse embryonic stem cells (mESCs) reveals that 5fC preferentially occurs at poised enhancers among other gene regulatory elements. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing
Platforms:
GPL16173 GPL13112
30 Samples
Download data: BED, TXT
Series
Accession:
GSE41545
ID:
200041545
2.

Illumina HiScanSQ (Mus musculus)

Organism:
Mus musculus
76 Series
652 Samples
Download data
Platform
Accession:
GPL16173
ID:
100016173
3.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
4.

Tdg -/- H3K4me1 ChIP'd, fCAB-Seq

Organism:
Mus musculus
Source name:
Tdg -/- H3K4me1 ChIP'd, fCAB-Seq
Platform:
GPL13112
Series:
GSE41545
Download data
Sample
Accession:
GSM1104081
ID:
301104081
5.

Tdg -/- H3K4me1 ChIP'd, Methyl-Seq

Organism:
Mus musculus
Source name:
Tdg -/- H3K4me1 ChIP'd, Methyl-Seq
Platform:
GPL13112
Series:
GSE41545
Download data
Sample
Accession:
GSM1104080
ID:
301104080
6.

Tdg fl/fl H3K4me1 ChIP'd, fCAB-Seq

Organism:
Mus musculus
Source name:
Tdg fl/fl H3K4me1 ChIP'd, fCAB-Seq
Platform:
GPL13112
Series:
GSE41545
Download data
Sample
Accession:
GSM1104079
ID:
301104079
7.

Tdg fl/fl H3K4me1 ChIP'd, Methyl-Seq

Organism:
Mus musculus
Source name:
Tdg fl/fl H3K4me1 ChIP'd, Methyl-Seq
Platform:
GPL13112
Series:
GSE41545
Download data
Sample
Accession:
GSM1104078
ID:
301104078
8.

5fC enriched DNA from Tdg fl/fl mouse EB cells, replicate 2

Organism:
Mus musculus
Source name:
5fC enriched DNA from Tdg fl/fl mouse EB cells
Platform:
GPL16173
Series:
GSE41545
Download data
Sample
Accession:
GSM1104077
ID:
301104077
9.

5fC enriched DNA from Tdg fl/fl mouse EB cells, replicate 1

Organism:
Mus musculus
Source name:
5fC enriched DNA from Tdg fl/fl mouse EB cells
Platform:
GPL16173
Series:
GSE41545
Download data
Sample
Accession:
GSM1104076
ID:
301104076
10.

5hmC enriched DNA from Tdg fl/fl mouse EB cells, replicate 2

Organism:
Mus musculus
Source name:
5hmC enriched DNA from Tdg fl/fl mouse EB cells
Platform:
GPL16173
Series:
GSE41545
Download data
Sample
Accession:
GSM1104075
ID:
301104075
11.

5hmC enriched DNA from Tdg fl/fl mouse EB cells, replicate 1

Organism:
Mus musculus
Source name:
5hmC enriched DNA from Tdg fl/fl mouse EB cells
Platform:
GPL16173
Series:
GSE41545
Download data
Sample
Accession:
GSM1104074
ID:
301104074
12.

Tdg -/- polyA RNA-Seq replicate 2

Organism:
Mus musculus
Source name:
Tdg -/- polyA RNA-Seq
Platform:
GPL16173
Series:
GSE41545
Download data
Sample
Accession:
GSM1019089
ID:
301019089
13.

Tdg -/- polyA RNA-Seq replicate 1

Organism:
Mus musculus
Source name:
Tdg -/- polyA RNA-Seq
Platform:
GPL16173
Series:
GSE41545
Download data
Sample
Accession:
GSM1019088
ID:
301019088
14.

Tdg fl/fl polyA RNA-Seq replicate 2

Organism:
Mus musculus
Source name:
Tdg fl/fl polyA RNA-Seq
Platform:
GPL16173
Series:
GSE41545
Download data
Sample
Accession:
GSM1019087
ID:
301019087
15.

Tdg fl/fl polyA RNA-Seq replicate 1

Organism:
Mus musculus
Source name:
Tdg fl/fl polyA RNA-Seq
Platform:
GPL16173
Series:
GSE41545
Download data
Sample
Accession:
GSM1019086
ID:
301019086
16.

Non-NaBH4 Control enrichment from Tdg fl/fl mouse ES cells b

Organism:
Mus musculus
Source name:
Non-NaBH4 Control enrichment from Tdg fl/fl mouse ES cells b
Platform:
GPL16173
Series:
GSE41545
Download data
Sample
Accession:
GSM1019085
ID:
301019085
17.

Non-NaBH4 Control enrichment from Tdg fl/fl mouse ES cells a

Organism:
Mus musculus
Source name:
Non-NaBH4 Control enrichment from Tdg fl/fl mouse ES cells a
Platform:
GPL16173
Series:
GSE41545
Download data
Sample
Accession:
GSM1019084
ID:
301019084
18.

Non-enriched input genomic DNA from Tdg -/- mouse ES cells

Organism:
Mus musculus
Source name:
Non-enriched input genomic DNA from Tdg -/- mouse ES cells
Platform:
GPL16173
Series:
GSE41545
Download data
Sample
Accession:
GSM1019083
ID:
301019083
19.

p300 ChIP-Seq from Tdg -/- mouse ES cells, replicate c

Organism:
Mus musculus
Source name:
p300 ChIP-Seq from Tdg -/- mouse ES cells, replicate c
Platform:
GPL16173
Series:
GSE41545
Download data
Sample
Accession:
GSM1019082
ID:
301019082
20.

p300 ChIP-Seq from Tdg -/- mouse ES cells, replicate b

Organism:
Mus musculus
Source name:
p300 ChIP-Seq from Tdg -/- mouse ES cells, replicate b
Platform:
GPL16173
Series:
GSE41545
Download data
Sample
Accession:
GSM1019081
ID:
301019081
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Supplemental Content

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