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Items: 14

1.

Foxp3 exploits a preexistent enhancer landscape for regulatory T cell lineage specification [ChIP-Seq]

(Submitter supplied) Regulatory T (Treg) cells, whose identity and function are defined by the transcription factor Foxp3, are indispensable for immune homeostasis. It is unclear whether Foxp3 exerts its Treg lineage specification function through active modification of the chromatin landscape and establishment of new enhancers or by exploiting a pre-existing enhancer landscape. Analysis of the chromatin accessibility of Foxp3-bound enhancers in Treg and Foxp3-negative T cells showed that Foxp3 was bound overwhelmingly to pre-accessible enhancers occupied by its cofactors in precursor cells or a structurally related predecessor. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL9250 GPL13112
11 Samples
Download data: TXT
Series
Accession:
GSE40684
ID:
200040684
2.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
3.

Illumina Genome Analyzer II (Mus musculus)

Platform
Accession:
GPL9250
ID:
100009250
4.

Treg Input Rep1

Organism:
Mus musculus
Source name:
Treg Input
Platform:
GPL9250
Series:
GSE40684 GSE40686
Download data
Sample
Accession:
GSM999181
ID:
300999181
5.

Treg Foxp3 ChIP Rep1 (Tech Rep1)

Organism:
Mus musculus
Source name:
Treg Foxp3 ChIP
Platform:
GPL9250
Series:
GSE40684 GSE40686
Download data
Sample
Accession:
GSM999179
ID:
300999179
6.

CD4 Cbfb ChIP

Organism:
Mus musculus
Source name:
CD4 Cbfb ChIP
Platform:
GPL13112
Series:
GSE40684 GSE40686
Download data
Sample
Accession:
GSM999189
ID:
300999189
7.

Treg Cbfb ChIP

Organism:
Mus musculus
Source name:
Treg Cbfb ChIP
Platform:
GPL13112
Series:
GSE40684 GSE40686
Download data: TXT
Sample
Accession:
GSM999188
ID:
300999188
8.

CD4 Ets1 ChIP

Organism:
Mus musculus
Source name:
CD4 Ets1 ChIP
Platform:
GPL13112
Series:
GSE40684 GSE40686
Download data: TXT
Sample
Accession:
GSM999187
ID:
300999187
9.

Treg Ets1 ChIP

Organism:
Mus musculus
Source name:
Treg Ets1 ChIP
Platform:
GPL13112
Series:
GSE40684 GSE40686
Download data: TXT
Sample
Accession:
GSM999186
ID:
300999186
10.

CD4 Elf1 ChIP

Organism:
Mus musculus
Source name:
CD4 Elf1 ChIP
Platform:
GPL13112
Series:
GSE40684 GSE40686
Download data: TXT
Sample
Accession:
GSM999185
ID:
300999185
11.

Treg Elf1 ChIP

Organism:
Mus musculus
Source name:
Treg Elf1 ChIP
Platform:
GPL13112
Series:
GSE40684 GSE40686
Download data: TXT
Sample
Accession:
GSM999184
ID:
300999184
12.

Treg Input Rep2

Organism:
Mus musculus
Source name:
Treg Input
Platform:
GPL13112
Series:
GSE40684 GSE40686
Download data
Sample
Accession:
GSM999183
ID:
300999183
13.

Treg Foxp3 ChIP Rep2

Organism:
Mus musculus
Source name:
Treg Foxp3 ChIP
Platform:
GPL13112
Series:
GSE40684 GSE40686
Download data
Sample
Accession:
GSM999182
ID:
300999182
14.

Treg Foxp3 ChIP Rep1 (Tech Rep2)

Organism:
Mus musculus
Source name:
Treg Foxp3 ChIP
Platform:
GPL13112
Series:
GSE40684 GSE40686
Download data
Sample
Accession:
GSM999180
ID:
300999180
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Supplemental Content

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