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Items: 9

1.

Genome-wide distribution of 5-formylcytosine in ES cells is associated with transcription and depends on TDG

(Submitter supplied) Methylation of cytosine in DNA (5mC) is an important epigenetic mark that is involved in the regulation of genome function. During early embryonic development in mammals, the DNA methylation landscape is dynamically reprogrammed in part through active demethylation. Recent advances have identified key players involved in active demethylation pathways, including oxidation of 5mC to 5-hydroxymethylcytosine (5hmC) and 5-formylcytosine (5fC) by the TET family of enzymes and excision of 5fC by the base excision repair enzyme thymine DNA glycosylase (TDG). more...
Organism:
Mus musculus
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL11002
7 Samples
Download data: BED
Series
Accession:
GSE40148
ID:
200040148
2.

Illumina Genome Analyzer IIx (Mus musculus)

Platform
Accession:
GPL11002
ID:
100011002
3.

EAR003_siRNA-tdg

Organism:
Mus musculus
Source name:
Embryonic stem cells, TDG siRNA, 5fC
Platform:
GPL11002
Series:
GSE40148
Download data: BED
Sample
Accession:
GSM986293
ID:
300986293
4.

EAR001_siRNA-control

Organism:
Mus musculus
Source name:
Embryonic stem cells, siRNA control, 5fC
Platform:
GPL11002
Series:
GSE40148
Download data: BED
Sample
Accession:
GSM986292
ID:
300986292
5.

BHAM480_siRNA-tdg

Organism:
Mus musculus
Source name:
Embryonic stem cells, TDG siRNA, 5fC
Platform:
GPL11002
Series:
GSE40148
Download data: BED
Sample
Accession:
GSM986291
ID:
300986291
6.

BHAM479_siRNA-control

Organism:
Mus musculus
Source name:
Embryonic stem cells, siRNA control, 5fC
Platform:
GPL11002
Series:
GSE40148
Download data: BED
Sample
Accession:
GSM986290
ID:
300986290
7.

BHAM470_WT

Organism:
Mus musculus
Source name:
Embryonic stem cells, WT, 5fC
Platform:
GPL11002
Series:
GSE40148
Download data: BED
Sample
Accession:
GSM986289
ID:
300986289
8.

BHAM385_WT

Organism:
Mus musculus
Source name:
Embryonic stem cells, WT, input
Platform:
GPL11002
Series:
GSE40148
Download data
Sample
Accession:
GSM986288
ID:
300986288
9.

BHAM359_WT

Organism:
Mus musculus
Source name:
Embryonic stem cells, WT, 5fC
Platform:
GPL11002
Series:
GSE40148
Download data: BED
Sample
Accession:
GSM986287
ID:
300986287
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Supplemental Content

db=gds|term=GSE40148[Accession]|query=1|qty=2|blobid=MCID_6699bd4356cb0a044e80959b|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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