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Items: 6

1.

Next-generation sequencing facilitates quantitative analysis of wild type and Bmp4f/f;Wnt1Cre tooth mesenchyme transcriptomes

(Submitter supplied) Previous studies have suggested that Bmp4 is a key Msx1-dependent mesenchymal odontogenic signal for driving tooth morphogenesis through the bud-to-cap transition. Whereas the bud stage tooth developmental arrest in Msx1-/- mutant mice was accompanied by reduction in mesenchymal Bmp4 mRNA expression, we show that depleting functional Bmp4 mRNAs in the tooth mesenchyme, through neural crest-specific gene inactivation in Bmp4f/f;Wnt1Cre mice, caused mandibular molar developmental arrest at the bud stage but allowed maxillary molars and incisors to develop to mineralized teeth. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13112
4 Samples
Download data: TXT
Series
Accession:
GSE39918
ID:
200039918
2.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
3.

Bmp4f/f;Wnt1Cre lower molar

Organism:
Mus musculus
Source name:
molar mesenchyme, lower molar, Bmp4 mutant
Platform:
GPL13112
Series:
GSE39918
Download data: TXT
Sample
Accession:
GSM981305
ID:
300981305
4.

Bmp4f/f;Wnt1Cre upper molar

Organism:
Mus musculus
Source name:
molar mesenchyme, upper molar, Bmp4 mutant
Platform:
GPL13112
Series:
GSE39918
Download data: TXT
Sample
Accession:
GSM981304
ID:
300981304
5.

Bmp4f/+ lower molar

Organism:
Mus musculus
Source name:
molar mesenchyme, lower molar, control
Platform:
GPL13112
Series:
GSE39918
Download data: TXT
Sample
Accession:
GSM981303
ID:
300981303
6.

Bmp4f/+ upper molar

Organism:
Mus musculus
Source name:
molar mesenchyme, upper molar, control
Platform:
GPL13112
Series:
GSE39918
Download data: TXT
Sample
Accession:
GSM981302
ID:
300981302
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Supplemental Content

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