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Items: 17

1.

Induced pluripotent stem cells from CINCA syndrome patients as a model for dissecting somatic mosaicism and drug discovery

(Submitter supplied) Chronic infantile neurological cutaneous and articular (CINCA) syndrome is an IL-1-driven autoinflammatory disorder caused mainly by NLRP3 mutations. The pathogenesis of CINCA syndrome patients who carry NLRP3 mutations as somatic mosaicism has not been precisely described because of the difficulty in separating individual cells based on the presence or absence of the mutation. Here, we report the generation of NLRP3-mutant and non-mutant induced pluripotent stem cell (iPSC) lines from two CINCA syndrome patients with somatic mosaicism, and describe their differentiation into macrophages (iPS-MPs). more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL13607
15 Samples
Download data: TXT
Series
Accession:
GSE38626
ID:
200038626
2.

Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Feature Number version)

(Submitter supplied) SurePrint G3 Human GE 8x60K Microarray Arrays of this design have barcodes that begin with 16028004 or 2528004. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. The ID column represents the Agilent Feature Extraction feature number. more...
Organism:
Homo sapiens
233 Series
2 Related Platforms
3749 Samples
Download data: TXT
Platform
Accession:
GPL13607
ID:
100013607
3.

fibroblast

Organism:
Homo sapiens
Source name:
fibroblast_CINCA
Platform:
GPL13607
Series:
GSE38626
Download data: TXT
Sample
Accession:
GSM946325
ID:
300946325
4.

ESC

Organism:
Homo sapiens
Source name:
ESC
Platform:
GPL13607
Series:
GSE38626
Download data: TXT
Sample
Accession:
GSM946324
ID:
300946324
5.

Macrophage_from_iPSC+NLRP3wt

Organism:
Homo sapiens
Source name:
iPSC
Platform:
GPL13607
Series:
GSE38626
Download data: TXT
Sample
Accession:
GSM946323
ID:
300946323
6.

Macrophage_from_iPSC+NLRP3mut

Organism:
Homo sapiens
Source name:
iPSC
Platform:
GPL13607
Series:
GSE38626
Download data: TXT
Sample
Accession:
GSM946322
ID:
300946322
7.

Normal-Macrophage-3

Organism:
Homo sapiens
Source name:
macrophage_normal
Platform:
GPL13607
Series:
GSE38626
Download data: TXT
Sample
Accession:
GSM946321
ID:
300946321
8.

Normal-Macrophage-2

Organism:
Homo sapiens
Source name:
macrophage_normal
Platform:
GPL13607
Series:
GSE38626
Download data: TXT
Sample
Accession:
GSM946320
ID:
300946320
9.

Normal-Macrophage-1

Organism:
Homo sapiens
Source name:
macrophage_normal
Platform:
GPL13607
Series:
GSE38626
Download data: TXT
Sample
Accession:
GSM946319
ID:
300946319
10.

Macrophage_from_ESC

Organism:
Homo sapiens
Source name:
ESC
Platform:
GPL13607
Series:
GSE38626
Download data: TXT
Sample
Accession:
GSM946318
ID:
300946318
11.

CINCA_NLRP3mut-Macrophage-3

Organism:
Homo sapiens
Source name:
iPSC_CINCA_NLRP3mut
Platform:
GPL13607
Series:
GSE38626
Download data: TXT
Sample
Accession:
GSM946317
ID:
300946317
12.

CINCA_NLRP3mut-Macrophage-2

Organism:
Homo sapiens
Source name:
iPSC_CINCA_NLRP3mut
Platform:
GPL13607
Series:
GSE38626
Download data: TXT
Sample
Accession:
GSM946316
ID:
300946316
13.

CINCA_NLRP3mut-Macrophage-1

Organism:
Homo sapiens
Source name:
iPSC_CINCA_NLRP3mut
Platform:
GPL13607
Series:
GSE38626
Download data: TXT
Sample
Accession:
GSM946315
ID:
300946315
14.

Macrophage_from_iPSC

Organism:
Homo sapiens
Source name:
iPSC
Platform:
GPL13607
Series:
GSE38626
Download data: TXT
Sample
Accession:
GSM946314
ID:
300946314
15.

CINCA_WildType-Macrophage-3

Organism:
Homo sapiens
Source name:
iPSC_CINCA_NLRP3wt
Platform:
GPL13607
Series:
GSE38626
Download data: TXT
Sample
Accession:
GSM946313
ID:
300946313
16.

CINCA_WildType-Macrophage-2

Organism:
Homo sapiens
Source name:
iPSC_CINCA_NLRP3wt
Platform:
GPL13607
Series:
GSE38626
Download data: TXT
Sample
Accession:
GSM946312
ID:
300946312
17.

CINCA_WildType-Macrophage-1

Organism:
Homo sapiens
Source name:
iPSC_CINCA_NLRP3wt
Platform:
GPL13607
Series:
GSE38626
Download data: TXT
Sample
Accession:
GSM946311
ID:
300946311
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