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Items: 10

1.

Resistance to Irreversible EGFR Tyrosine Kinase Inhibitors through a Multistep Mechanism Involving the IGF1R Pathway

(Submitter supplied) The clinical efficacy of EGFR kinase inhibitors gefitinib and erlotinib is limited by the development of drug resistance. The most common mechanism of drug resistance is the secondary EGFR T790M mutation. Strategies to overcome EGFR T790M mediated drug resistance include the use of mutant selective EGFR inhibitors, including WZ4002, or by the use of high concentrations of irreversible quinazoline EGFR inhibitors such as PF299804. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL571
8 Samples
Download data: CEL
Series
Accession:
GSE38404
ID:
200038404
2.

[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Human Genome U133A 2.0 Array is a single array representing 14,500 well-characterized human genes that can be used to explore human biology and disease processes. more...
Organism:
Homo sapiens
84 DataSets
638 Series
12 Related Platforms
24352 Samples
Download data
Platform
Accession:
GPL571
ID:
100000571
3.

PFR32_1_rep3

Organism:
Homo sapiens
Source name:
NSCLC cells
Platform:
GPL571
Series:
GSE38404
Download data: CEL
Sample
Accession:
GSM941556
ID:
300941556
4.

PFR32_1_rep2

Organism:
Homo sapiens
Source name:
NSCLC cells
Platform:
GPL571
Series:
GSE38404
Download data: CEL
Sample
Accession:
GSM941555
ID:
300941555
5.

PFR32_1_rep1

Organism:
Homo sapiens
Source name:
NSCLC cells
Platform:
GPL571
Series:
GSE38404
Download data: CEL
Sample
Accession:
GSM941554
ID:
300941554
6.

PFR31_1_rep3

Organism:
Homo sapiens
Source name:
NSCLC cells
Platform:
GPL571
Series:
GSE38404
Download data: CEL
Sample
Accession:
GSM941553
ID:
300941553
7.

PFR31_1_rep2

Organism:
Homo sapiens
Source name:
NSCLC cells
Platform:
GPL571
Series:
GSE38404
Download data: CEL
Sample
Accession:
GSM941552
ID:
300941552
8.

PFR31_1_rep1

Organism:
Homo sapiens
Source name:
NSCLC cells
Platform:
GPL571
Series:
GSE38404
Download data: CEL
Sample
Accession:
GSM941551
ID:
300941551
9.

PC9_1_rep2

Organism:
Homo sapiens
Source name:
NSCLC cells
Platform:
GPL571
Series:
GSE38404
Download data: CEL
Sample
Accession:
GSM941550
ID:
300941550
10.

PC9_1_rep1

Organism:
Homo sapiens
Source name:
NSCLC cells
Platform:
GPL571
Series:
GSE38404
Download data: CEL
Sample
Accession:
GSM941549
ID:
300941549
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Supplemental Content

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