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Items: 6

1.

DEEP SEQUENCING OF MODELS OF BREAST DUCTAL CARCINOMA IN SITU REVEALS ALDH5A1 AS A NOVEL POTENTIAL THERAPEUTIC TARGET

(Submitter supplied) We attempted to identify alterations in gene expression that occur during the progression from normal breast to ductal carcinoma in situ (DCIS) with the aim to elucidate significant genes and pathways underlying the premalignant transformation. To determine the expression changes that are common to multiple DCIS models (MCF10.DCIS, SUM102 and SUM225) and normal mammary epithelial cells (MCF10A), we grew the cells in three dimensional overlay culture with reconstituted basement membrane and used the extracted RNA for 76 cycles of deep sequencing (mRNA-Seq) using Illumina Genome Analyzer GAIIx. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL10999
4 Samples
Download data: BED
Series
Accession:
GSE36863
ID:
200036863
2.

Illumina Genome Analyzer IIx (Homo sapiens)

Platform
Accession:
GPL10999
ID:
100010999
3.

Sum225

Organism:
Homo sapiens
Source name:
ductal carcinoma in situ cells
Platform:
GPL10999
Series:
GSE36863
Download data: BED
Sample
Accession:
GSM903306
ID:
300903306
4.

Sum102

Organism:
Homo sapiens
Source name:
ductal carcinoma in situ cells
Platform:
GPL10999
Series:
GSE36863
Download data: BED
Sample
Accession:
GSM903305
ID:
300903305
5.

DCIS

Organism:
Homo sapiens
Source name:
ductal carcinoma in situ cells
Platform:
GPL10999
Series:
GSE36863
Download data: BED
Sample
Accession:
GSM903304
ID:
300903304
6.

MCF10A

Organism:
Homo sapiens
Source name:
normal mammary epithelial cells
Platform:
GPL10999
Series:
GSE36863
Download data: BED
Sample
Accession:
GSM903303
ID:
300903303
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Supplemental Content

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