GSE35496[Accession] - GEO DataSets - NCBI

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Select item 2000354961.

ChIP-Seq of Sox2 and Brn2 in ESCs, NPCs, and differentiating ESCs

(Submitter supplied) We analyzed the genome-wide binding of Sox2 and POU factor partner factors, Oct4 in ESCs (using published datasets PMID:18692474 and GSM307137, GSM307154, GSM307155) and Brn2 in NPCs. We found that Sox2 and Oct4 co-occupied a large subset of promoters and enhancers in ESCs, but that Sox2 and Brn2 co-occupy predominantly enhancers. Further, we overexpressed Brn2 in differentiating ESCs and showed that ectopic Brn2 recruited Sox2 to NPC-specific targets, resulting in skewed differentiation towards the neural lineage.

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL9250 GPL13112
30 Samples

Download data: WIG

Series

Accession:: GSE35496

ID:: 200035496

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 1000131122.

Illumina HiSeq 2000 (Mus musculus)

Organism:: Mus musculus

8080 Series
183843 Samples

Platform

Accession:: GPL13112

ID:: 100013112

Select item 1000092503.

Illumina Genome Analyzer II (Mus musculus)

Organism:: Mus musculus

800 Series
5946 Samples

Platform

Accession:: GPL9250

ID:: 100009250

Select item 3010503154.

H3 ChIP-Seq Day2 rtta, rep2

Organism:: Mus musculus

Source name:: Day2 differentiating rtta ESCs, H3 ChIP

Platform:: GPL13112
Series:: GSE35496

Sample

Accession:: GSM1050315

ID:: 301050315

SRA Run Selector

Select item 3010503145.

H3K27Ac ChIP-Seq Day2 rtta, rep2

Organism:: Mus musculus

Source name:: Day2 differentiating rtta ESCs, H3K27Ac ChIP

Platform:: GPL13112
Series:: GSE35496

Sample

Accession:: GSM1050314

ID:: 301050314

SRA Run Selector

Select item 3010503136.

H3 ChIP-Seq Day2 rtta, rep1

Organism:: Mus musculus

Source name:: Day2 differentiating rtta ESCs, H3 ChIP

Platform:: GPL13112
Series:: GSE35496

Sample

Accession:: GSM1050313

ID:: 301050313

SRA Run Selector

Select item 3010503127.

H3K27Ac ChIP-Seq Day2 rtta, rep1

Organism:: Mus musculus

Source name:: Day2 differentiating rtta ESCs, H3K27Ac ChIP

Platform:: GPL13112
Series:: GSE35496

Sample

Accession:: GSM1050312

ID:: 301050312

SRA Run Selector

Select item 3010503118.

H3K4me1 ChIP-Seq Day2 rtta

Organism:: Mus musculus

Source name:: Day2 differentiating rtta ESCs, H3K4me1 ChIP

Platform:: GPL13112
Series:: GSE35496

Sample

Accession:: GSM1050311

ID:: 301050311

SRA Run Selector

Select item 3010503109.

H3 ChIP-Seq Day2 TetoBrn2, rep2

Organism:: Mus musculus

Source name:: Day2 differentiating Teto-Brn2 ESCs, H3 ChIP

Platform:: GPL13112
Series:: GSE35496

Sample

Accession:: GSM1050310

ID:: 301050310

SRA Run Selector

Select item 30105030910.

H3K27Ac ChIP-Seq Day2 TetoBrn2, rep2

Organism:: Mus musculus

Source name:: Day2 differentiating Teto-Brn2 ESCs, H3K27Ac ChIP

Platform:: GPL13112
Series:: GSE35496

Sample

Accession:: GSM1050309

ID:: 301050309

SRA Run Selector

Select item 30105030811.

H3 ChIP-Seq Day2 TetoBrn2, rep1

Organism:: Mus musculus

Source name:: Day2 differentiating Teto-Brn2 ESCs, H3 ChIP

Platform:: GPL13112
Series:: GSE35496

Sample

Accession:: GSM1050308

ID:: 301050308

SRA Run Selector

Select item 30105030712.

H3K27Ac ChIP-Seq Day2 TetoBrn2, rep1

Organism:: Mus musculus

Source name:: Day2 differentiating Teto-Brn2 ESCs, H3K27Ac ChIP

Platform:: GPL13112
Series:: GSE35496

Sample

Accession:: GSM1050307

ID:: 301050307

SRA Run Selector

Select item 30105030613.

H3K4me1 ChIP-Seq Day2 TetoBrn2

Organism:: Mus musculus

Source name:: Day2 differentiating Teto-Brn2 ESCs, H3K4me1 ChIP

Platform:: GPL13112
Series:: GSE35496

Sample

Accession:: GSM1050306

ID:: 301050306

SRA Run Selector

Select item 30105030514.

Day2 rtta WCE Seq, rep2

Organism:: Mus musculus

Source name:: Day2 differentiating rtta ESCs, WCE

Platform:: GPL13112
Series:: GSE35496

Sample

Accession:: GSM1050305

ID:: 301050305

SRA Run Selector

Select item 30105030415.

Sox2 ChIP-Seq Day2 rtta, rep2

Organism:: Mus musculus

Source name:: Day2 differentiating rtta ESCs, Sox2 ChIP

Platform:: GPL13112
Series:: GSE35496

Sample

Accession:: GSM1050304

ID:: 301050304

SRA Run Selector

Select item 30105030316.

Brn2 ChIP-Seq Day2 rtta, rep2

Organism:: Mus musculus

Source name:: Day2 differentiating rtta ESCs, Brn2 ChIP

Platform:: GPL13112
Series:: GSE35496

Sample

Accession:: GSM1050303

ID:: 301050303

SRA Run Selector

Select item 30105030217.

Day2 TetoBrn2 WCE Seq, rep2

Organism:: Mus musculus

Source name:: Day2 differentiating Teto-Brn2 ESCs, WCE

Platform:: GPL13112
Series:: GSE35496

Sample

Accession:: GSM1050302

ID:: 301050302

SRA Run Selector

Select item 30105030118.

Sox2 ChIP-Seq Day2 TetoBrn2, rep2

Organism:: Mus musculus

Source name:: Day2 differentiating Teto-Brn2 ESCs, Sox2 ChIP

Platform:: GPL13112
Series:: GSE35496

Sample

Accession:: GSM1050301

ID:: 301050301

SRA Run Selector

Select item 30105030019.

Brn2 ChIP-Seq Day2 TetoBrn2, rep2

Organism:: Mus musculus

Source name:: Day2 differentiating Teto-Brn2 ESCs, Brn2 ChIP

Platform:: GPL13112
Series:: GSE35496

Sample

Accession:: GSM1050300

ID:: 301050300

SRA Run Selector

Select item 30105029920.

Day2 rtta WCE Seq, rep1

Organism:: Mus musculus

Source name:: Day2 differentiating rtta ESCs, WCE

Platform:: GPL13112
Series:: GSE35496

Sample

Accession:: GSM1050299

ID:: 301050299

SRA Run Selector

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