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Items: 11

1.

Osr2 functions as a mechanical checkpoint to augment CD8+ T cell exhaustion [YODA1_vs_DMSO_CutnTag_CD8]

(Submitter supplied) The alteration in extracellular matrix (ECM) architecture and stiffness becomes one of the hallmarks of cancer. Whether the mechanical property of ECM contributes to the functionality of CD8+ T cells, a key component of anti-tumor response, remains largely unknown. Here we report that mechanical stress drives T cell exhaustion program via Osr2, a transcription factor that had been poorly investigated in T cells. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL24247
9 Samples
Download data: BW
Series
Accession:
GSE260449
ID:
200260449
2.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
3.

IgG_rep1

Organism:
Mus musculus
Source name:
primary CD8 T cell
Platform:
GPL24247
Series:
GSE260449
Download data: BW
Sample
Accession:
GSM8117422
ID:
308117422
4.

P300_YODA1_rep2

Organism:
Mus musculus
Source name:
primary CD8 T cell
Platform:
GPL24247
Series:
GSE260449
Download data: BW
Sample
Accession:
GSM8117421
ID:
308117421
5.

P300_YODA1_rep1

Organism:
Mus musculus
Source name:
primary CD8 T cell
Platform:
GPL24247
Series:
GSE260449
Download data: BW
Sample
Accession:
GSM8117420
ID:
308117420
6.

P300_DMSO_rep2

Organism:
Mus musculus
Source name:
primary CD8 T cell
Platform:
GPL24247
Series:
GSE260449
Download data: BW
Sample
Accession:
GSM8117419
ID:
308117419
7.

P300_DMSO_rep1

Organism:
Mus musculus
Source name:
primary CD8 T cell
Platform:
GPL24247
Series:
GSE260449
Download data: BW
Sample
Accession:
GSM8117418
ID:
308117418
8.

CREB_YODA1_rep2

Organism:
Mus musculus
Source name:
primary CD8 T cell
Platform:
GPL24247
Series:
GSE260449
Download data: BW
Sample
Accession:
GSM8117417
ID:
308117417
9.

CREB_YODA1_rep1

Organism:
Mus musculus
Source name:
primary CD8 T cell
Platform:
GPL24247
Series:
GSE260449
Download data: BW
Sample
Accession:
GSM8117416
ID:
308117416
10.

CREB_DMSO_rep2

Organism:
Mus musculus
Source name:
primary CD8 T cell
Platform:
GPL24247
Series:
GSE260449
Download data: BW
Sample
Accession:
GSM8117415
ID:
308117415
11.

CREB_DMSO_rep1

Organism:
Mus musculus
Source name:
primary CD8 T cell
Platform:
GPL24247
Series:
GSE260449
Download data: BW
Sample
Accession:
GSM8117414
ID:
308117414
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Supplemental Content

db=gds|term=GSE260449[Accession]|query=1|qty=2|blobid=MCID_66e98388b3438a05768149c9|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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