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Items: 8

1.

GDNF/GFRA1 signaling contributes to chemo- and radioresistance in glioblastoma

(Submitter supplied) Glioblastoma (GBM) is the most common primary brain tumor in adults, characterized by an inherent aggressivity and resistance to treatment leading to poor prognoses. While some resistance mechanisms have been elucidated, a deeper understanding of these mechanisms is needed to increase therapeutic efficacy. In this study we first discovered glial-cell derived neurotrophic factor (GDNF) to be upregulated in patient-derived glioblastoma spheroid cultures after chemotherapeutic temozolomide (TMZ) treatment, through RNA-Seq experiments. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18460
6 Samples
Download data: TXT, XLSX
Series
Accession:
GSE255581
ID:
200255581
2.

Illumina HiSeq 1500 (Homo sapiens)

Platform
Accession:
GPL18460
ID:
100018460
3.

T111 Control cells

Organism:
Homo sapiens
Source name:
Primary GBM
Platform:
GPL18460
Series:
GSE255581
Download data
Sample
Accession:
GSM8075536
ID:
308075536
4.

T111 GBM cells after TMZ treatment

Organism:
Homo sapiens
Source name:
Primary GBM
Platform:
GPL18460
Series:
GSE255581
Download data
Sample
Accession:
GSM8075535
ID:
308075535
5.

T86 control cells

Organism:
Homo sapiens
Source name:
Primary GBM
Platform:
GPL18460
Series:
GSE255581
Download data
Sample
Accession:
GSM8075534
ID:
308075534
6.

T86 GBM cells after TMZ treatment

Organism:
Homo sapiens
Source name:
Primary GBM
Platform:
GPL18460
Series:
GSE255581
Download data
Sample
Accession:
GSM8075533
ID:
308075533
7.

Control T78 GBM cells

Organism:
Homo sapiens
Source name:
Primary GBM
Platform:
GPL18460
Series:
GSE255581
Download data
Sample
Accession:
GSM8075532
ID:
308075532
8.

T78 GBM cells afer TMZ treatment

Organism:
Homo sapiens
Source name:
Primary GBM
Platform:
GPL18460
Series:
GSE255581
Download data
Sample
Accession:
GSM8075531
ID:
308075531
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Supplemental Content

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