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Items: 5

1.

Age-related epithelial defects limit thymic function and regeneration [single cell; Foxn1Lin]

(Submitter supplied) The thymus is essential for establishing adaptive immunity yet undergoes age-related involution that leads to compromised immune responsiveness. The thymus is also extremely sensitive to acute insult and although capable of regeneration, this capacity declines with age for unknown reasons. We applied single-cell and spatial transcriptomics, lineage-tracing and advanced imaging to define age-related changes in non-hematopoietic stromal cells and discovered the emergence of two atypical thymic epithelial cell (TEC) states. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
3 Samples
Download data: CSV, H5, H5AD, MTX, TSV
Series
Accession:
GSE249753
ID:
200249753

Full text in PMC Similar studies

2.

Illumina NovaSeq 6000 (Mus musculus)

Organism:
Mus musculus
13697 Series
687320 Samples
Download data
Platform
Accession:
GPL24247
ID:
100024247

3.

20-mo CD45- thymic stoma cells - wild type - male [singe cell]

Organism:
Mus musculus
Source name:
thymus
Platform:
GPL24247
Series:
GSE240020 GSE249753
Download data: CSV, H5, MTX, TSV
Sample
Accession:
GSM7963648
ID:
307963648

SRA Run Selector

4.

20-mo CD45- thymic stoma cells - Foxn1Lin - male [singe cell]

Organism:
Mus musculus
Source name:
thymus
Platform:
GPL24247
Series:
GSE240020 GSE249753
Download data: CSV, H5, MTX, TSV
Sample
Accession:
GSM7963647
ID:
307963647

SRA Run Selector

5.

20-mo CD45- thymic stoma cells - Foxn1Lin - female [singe cell]

Organism:
Mus musculus
Source name:
thymus
Platform:
GPL24247
Series:
GSE240020 GSE249753
Download data: CSV, H5, MTX, TSV
Sample
Accession:
GSM7963646
ID:
307963646

SRA Run Selector

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db=gds|term=GSE249753[Accession]|query=1|qty=2|blobid=MCID_66fe6a7e75ef196929385c2c|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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