GSE248206[Accession] - GEO DataSets - NCBI

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Items: 17

Select item 2002482061.

Lineage-specific intolerance to oncogenic drivers restricts histological transformation [ATAC-Seq]

(Submitter supplied) Lung adenocarcinoma (LUAD) and small cell lung cancer (SCLC) are thought to originate from different epithelial cell types in the lung. Intriguingly, LUAD can histologically transform into SCLC following treatment with targeted therapies. Here we designed models to follow the conversion of LUAD to SCLC and found the barrier to histological transformation converges on tolerance to Myc, which we implicate as a lineage-specific driver of the pulmonary neuroendocrine cell. more...

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL17021
15 Samples

Download data: BROADPEAK, TXT

Series

Accession:: GSE248206

ID:: 200248206

PubMed Full text in PMC Similar studies

Select item 1000170212.

Illumina HiSeq 2500 (Mus musculus)

Organism:: Mus musculus

11017 Series
297561 Samples

Platform

Accession:: GPL17021

ID:: 100017021

Select item 3079083813.

Lung, AT2 origin, Pten H1047R, chromatin, rep 2

Organism:: Mus musculus

Source name:: Lung

Platform:: GPL17021
Series:: GSE248206 GSE248207

Download data: BROADPEAK

Sample

Accession:: GSM7908381

ID:: 307908381

SRA Run Selector

Select item 3079083804.

Lung, AT2 origin, Pten H1047R, chromatin, rep 1

Organism:: Mus musculus

Source name:: Lung

Platform:: GPL17021
Series:: GSE248206 GSE248207

Download data: BROADPEAK

Sample

Accession:: GSM7908380

ID:: 307908380

SRA Run Selector

Select item 3079083795.

Lung, AT2 origin, Pten E545K, chromatin, rep 2

Organism:: Mus musculus

Source name:: Lung

Platform:: GPL17021
Series:: GSE248206 GSE248207

Download data: BROADPEAK

Sample

Accession:: GSM7908379

ID:: 307908379

SRA Run Selector

Select item 3079083786.

Lung, AT2 origin, Pten E545K, chromatin, rep 1

Organism:: Mus musculus

Source name:: Lung

Platform:: GPL17021
Series:: GSE248206 GSE248207

Download data: BROADPEAK

Sample

Accession:: GSM7908378

ID:: 307908378

SRA Run Selector

Select item 3079083777.

Lung, AT2 origin, Pten loss, chromatin, rep 2

Organism:: Mus musculus

Source name:: Lung

Platform:: GPL17021
Series:: GSE248206 GSE248207

Download data: BROADPEAK

Sample

Accession:: GSM7908377

ID:: 307908377

SRA Run Selector

Select item 3079083768.

Lung, AT2 origin, Pten loss, chromatin, rep 1

Organism:: Mus musculus

Source name:: Lung

Platform:: GPL17021
Series:: GSE248206 GSE248207

Download data: BROADPEAK

Sample

Accession:: GSM7908376

ID:: 307908376

SRA Run Selector

Select item 3079083759.

Lung, AT2 origin, WT, chromatin, rep 2

Organism:: Mus musculus

Source name:: Lung

Platform:: GPL17021
Series:: GSE248206 GSE248207

Download data: BROADPEAK

Sample

Accession:: GSM7908375

ID:: 307908375

SRA Run Selector

Select item 30790837410.

Lung, AT2 origin, WT, chromatin, rep 1

Organism:: Mus musculus

Source name:: Lung

Platform:: GPL17021
Series:: GSE248206 GSE248207

Download data: BROADPEAK

Sample

Accession:: GSM7908374

ID:: 307908374

SRA Run Selector

Select item 30790837311.

Lung, de novo LUAD, chromatin, rep 3

Organism:: Mus musculus

Source name:: Lung

Platform:: GPL17021
Series:: GSE248206 GSE248207

Download data: BROADPEAK

Sample

Accession:: GSM7908373

ID:: 307908373

SRA Run Selector

Select item 30790837212.

Lung, de novo LUAD, chromatin, rep 2

Organism:: Mus musculus

Source name:: Lung

Platform:: GPL17021
Series:: GSE248206 GSE248207

Download data: BROADPEAK

Sample

Accession:: GSM7908372

ID:: 307908372

SRA Run Selector

Select item 30790837113.

Lung, de novo LUAD, chromatin, rep 1

Organism:: Mus musculus

Source name:: Lung

Platform:: GPL17021
Series:: GSE248206 GSE248207

Download data: BROADPEAK

Sample

Accession:: GSM7908371

ID:: 307908371

SRA Run Selector

Select item 30790837014.

Lung, AT2 origin, SCLC genotype, chromatin, pooled

Organism:: Mus musculus

Source name:: Lung

Platform:: GPL17021
Series:: GSE248206 GSE248207

Download data: BROADPEAK

Sample

Accession:: GSM7908370

ID:: 307908370

SRA Run Selector

Select item 30790836915.

Lung, de novo SCLC, chromatin, rep 2

Organism:: Mus musculus

Source name:: Lung

Platform:: GPL17021
Series:: GSE248206 GSE248207

Download data: BROADPEAK

Sample

Accession:: GSM7908369

ID:: 307908369

SRA Run Selector

Select item 30790836816.

Lung, de novo SCLC, chromatin, rep 1

Organism:: Mus musculus

Source name:: Lung

Platform:: GPL17021
Series:: GSE248206 GSE248207

Download data: BROADPEAK

Sample

Accession:: GSM7908368

ID:: 307908368

SRA Run Selector

Select item 30790836717.

Lung, PNEC origin, LUAD genotype, chromatin, pooled

Organism:: Mus musculus

Source name:: Lung

Platform:: GPL17021
Series:: GSE248206 GSE248207

Download data: BROADPEAK

Sample

Accession:: GSM7908367

ID:: 307908367

SRA Run Selector

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