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Items: 1 to 20 of 23

1.

Antiepileptic medication induces homeostatic synaptic plasticity in pyramidal neurons of the adult human neocortex

(Submitter supplied) Homeostatic synaptic plasticity serves to maintain neuronal function within a dynamic range, compensating for perturbations in network activity. While coordinated structural and functional changes at synaptic sites play a crucial role in adaptive processes, the specific regulatory mechanisms and biological relevance of homeostatic plasticity in the human brain warrant further investigation. In this study, we investigated the effects of neural network silencing, achieved through pharmacological inhibition of voltage-gated sodium channels or glutamatergic neurotransmission – common targets of antiepileptic medication – on functional and structural properties of murine and human cortical tissue. more...
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL24247 GPL24676
20 Samples
Download data: TXT
Series
Accession:
GSE244095
ID:
200244095

2.

Illumina NovaSeq 6000 (Homo sapiens)

Organism:
Homo sapiens
16162 Series
916364 Samples
Download data
Platform
Accession:
GPL24676
ID:
100024676

3.

Illumina NovaSeq 6000 (Mus musculus)

Organism:
Mus musculus
13438 Series
684161 Samples
Download data
Platform
Accession:
GPL24247
ID:
100024247

4.

Human Neocortex, CONTROL-1, biol rep 1

Organism:
Homo sapiens
Source name:
Brain, adult, neocortex
Platform:
GPL24676
Series:
GSE244095
Download data: TXT
Sample
Accession:
GSM7806573
ID:
307806573

SRA Run Selector

5.

Human Neocortex, AED-4, biol rep 4

Organism:
Homo sapiens
Source name:
Brain, adult, neocortex
Platform:
GPL24676
Series:
GSE244095
Download data: TXT
Sample
Accession:
GSM7806572
ID:
307806572

SRA Run Selector

6.

Human Neocortex, AED-3, biol rep 3

Organism:
Homo sapiens
Source name:
Brain, adult, neocortex
Platform:
GPL24676
Series:
GSE244095
Download data: TXT
Sample
Accession:
GSM7806571
ID:
307806571

SRA Run Selector

7.

Human Neocortex, AED-2, biol rep 2

Organism:
Homo sapiens
Source name:
Brain, adult, neocortex
Platform:
GPL24676
Series:
GSE244095
Download data: TXT
Sample
Accession:
GSM7806570
ID:
307806570

SRA Run Selector

8.

Human Neocortex, AED-1, biol rep 1

Organism:
Homo sapiens
Source name:
Brain, adult, neocortex
Platform:
GPL24676
Series:
GSE244095
Download data: TXT
Sample
Accession:
GSM7806569
ID:
307806569

SRA Run Selector

9.

Mouse mPFC, LTG-3_biol rep 3

Organism:
Mus musculus
Source name:
Brain, adult, medial prefrontal cortex
Platform:
GPL24247
Series:
GSE244095
Download data: TXT
Sample
Accession:
GSM7806588
ID:
307806588

SRA Run Selector

10.

Mouse mPFC, LTG-2_biol rep 2

Organism:
Mus musculus
Source name:
Brain, adult, medial prefrontal cortex
Platform:
GPL24247
Series:
GSE244095
Download data: TXT
Sample
Accession:
GSM7806587
ID:
307806587

SRA Run Selector

11.

Mouse mPFC, LTG-1_biol rep 1

Organism:
Mus musculus
Source name:
Brain, adult, medial prefrontal cortex
Platform:
GPL24247
Series:
GSE244095
Download data: TXT
Sample
Accession:
GSM7806586
ID:
307806586

SRA Run Selector

12.

Mouse mPFC, CONTROL-4_biol rep 4

Organism:
Mus musculus
Source name:
Brain, adult, medial prefrontal cortex
Platform:
GPL24247
Series:
GSE244095
Download data: TXT
Sample
Accession:
GSM7806585
ID:
307806585

SRA Run Selector

13.

Mouse mPFC, CONTROL-3_biol rep 3

Organism:
Mus musculus
Source name:
Brain, adult, medial prefrontal cortex
Platform:
GPL24247
Series:
GSE244095
Download data: TXT
Sample
Accession:
GSM7806584
ID:
307806584

SRA Run Selector

14.

Mouse mPFC, CONTROL-2_biol rep 2

Organism:
Mus musculus
Source name:
Brain, adult, medial prefrontal cortex
Platform:
GPL24247
Series:
GSE244095
Download data: TXT
Sample
Accession:
GSM7806583
ID:
307806583

SRA Run Selector

15.

Mouse mPFC, CONTROL-1_biol rep 1

Organism:
Mus musculus
Source name:
Brain, adult, medial prefrontal cortex
Platform:
GPL24247
Series:
GSE244095
Download data: TXT
Sample
Accession:
GSM7806582
ID:
307806582

SRA Run Selector

16.

Mouse OTC, TTX-4, biol rep 4

Organism:
Mus musculus
Source name:
Brain, organotypic entorhino-hippocampal culture
Platform:
GPL24247
Series:
GSE244095
Download data: TXT
Sample
Accession:
GSM7806581
ID:
307806581

SRA Run Selector

17.

Mouse OTC, TTX-3, biol rep 3

Organism:
Mus musculus
Source name:
Brain, organotypic entorhino-hippocampal culture
Platform:
GPL24247
Series:
GSE244095
Download data: TXT
Sample
Accession:
GSM7806580
ID:
307806580

SRA Run Selector

18.

Mouse OTC, TTX-2, biol rep 2

Organism:
Mus musculus
Source name:
Brain, organotypic entorhino-hippocampal culture
Platform:
GPL24247
Series:
GSE244095
Download data: TXT
Sample
Accession:
GSM7806579
ID:
307806579

SRA Run Selector

19.

Mouse OTC, TTX-1, biol rep 1

Organism:
Mus musculus
Source name:
Brain, organotypic entorhino-hippocampal culture
Platform:
GPL24247
Series:
GSE244095
Download data: TXT
Sample
Accession:
GSM7806578
ID:
307806578

SRA Run Selector

20.

Mouse OTC, control-4, biol rep 4

Organism:
Mus musculus
Source name:
Brain, organotypic entorhino-hippocampal culture
Platform:
GPL24247
Series:
GSE244095
Download data: TXT
Sample
Accession:
GSM7806577
ID:
307806577

SRA Run Selector

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