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Items: 14

1.

Prophilactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction.

(Submitter supplied) Senescent cells accumulate in organisms over time as a result of tissue damage and impaired immune surveillance and are thought to contribute to age-related tissue decline1,2. In agreement, genetic ablation studies reveal that elimination of senescent cells from aged tissues can ameliorate various age-related pathologies, including metabolic dysfunction and decreased physical fitness3-7. While small-molecule drugs capable of eliminating senescent cells (known as ‘senolytics’) partially replicate these phenotypes, many have uncertain mechanisms of action and all require continuous administration to be effective. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
12 Samples
Download data: H5
Series
Accession:
GSE243616
ID:
200243616
2.

Illumina NextSeq 500 (Mus musculus)

Platform
Accession:
GPL19057
ID:
100019057
3.

Amor_P2_uPAR_positive

Organism:
Mus musculus
Source name:
Pancreas
Platform:
GPL19057
Series:
GSE243616
Download data
Sample
Accession:
GSM7791918
ID:
307791918
4.

Amor_P1_uPAR_positive

Organism:
Mus musculus
Source name:
Pancreas
Platform:
GPL19057
Series:
GSE243616
Download data
Sample
Accession:
GSM7791917
ID:
307791917
5.

Amor_AT1_uPAR_positive

Organism:
Mus musculus
Source name:
Gonadal adipose tissue
Platform:
GPL19057
Series:
GSE243616
Download data
Sample
Accession:
GSM7791916
ID:
307791916
6.

Amor_AT3_uPAR_positive

Organism:
Mus musculus
Source name:
Gonadal adipose tissue
Platform:
GPL19057
Series:
GSE243616
Download data
Sample
Accession:
GSM7791915
ID:
307791915
7.

Amor_L3_uPAR_positive

Organism:
Mus musculus
Source name:
Liver
Platform:
GPL19057
Series:
GSE243616
Download data
Sample
Accession:
GSM7791914
ID:
307791914
8.

Amor_L1_uPAR_positive

Organism:
Mus musculus
Source name:
Liver
Platform:
GPL19057
Series:
GSE243616
Download data
Sample
Accession:
GSM7791913
ID:
307791913
9.

Amor_P2_uPAR_negative

Organism:
Mus musculus
Source name:
Pancreas
Platform:
GPL19057
Series:
GSE243616
Download data
Sample
Accession:
GSM7791912
ID:
307791912
10.

Amor_P1_uPAR_negative

Organism:
Mus musculus
Source name:
Pancreas
Platform:
GPL19057
Series:
GSE243616
Download data
Sample
Accession:
GSM7791911
ID:
307791911
11.

Amor_AT1_uPAR_negative

Organism:
Mus musculus
Source name:
Gonadal adipose tissue
Platform:
GPL19057
Series:
GSE243616
Download data
Sample
Accession:
GSM7791910
ID:
307791910
12.

Amor_AT3_uPAR_negative

Organism:
Mus musculus
Source name:
Gonadal adipose tissue
Platform:
GPL19057
Series:
GSE243616
Download data
Sample
Accession:
GSM7791909
ID:
307791909
13.

Amor_L3_uPAR_negative

Organism:
Mus musculus
Source name:
Liver
Platform:
GPL19057
Series:
GSE243616
Download data
Sample
Accession:
GSM7791908
ID:
307791908
14.

Amor_L1_uPAR_negative

Organism:
Mus musculus
Source name:
Liver
Platform:
GPL19057
Series:
GSE243616
Download data
Sample
Accession:
GSM7791907
ID:
307791907
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Supplemental Content

db=gds|term=GSE243616[Accession]|query=1|qty=2|blobid=MCID_661b4561e3fccf293782b4b5|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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