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Items: 4

1.

A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival [ATAC-seq]

(Submitter supplied) Gene deserts spanning more than 500kb of non-protein coding genomic sequence are considered evolutionarily ancient and stable and are enriched in the vicinity of developmental regulator genes (Ovcharenko 2005). These extensive genomic regions typically harbor numerous conserved elements with predicted gene regulatory potential pointing to critical tissue-specific functions during development. Nevertheless, the biological necessity and underlying funtional enhancer landscapes of most gene deserts near developmental transcription factors (TFs) remain unknown, and it is unclear how precise pleiotropic expression patterns emerge from gene desert sequence. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL21103
2 Samples
Download data: BW, NARROWPEAK
Series
Accession:
GSE232882
ID:
200232882
2.

Illumina HiSeq 4000 (Mus musculus)

Platform
Accession:
GPL21103
ID:
100021103
3.

ATAC_H_E115-WT_rep2

Organism:
Mus musculus
Source name:
Embryonic Heart
Platform:
GPL21103
Series:
GSE232882 GSE232887
Download data: BW, NARROWPEAK
Sample
Accession:
GSM7385433
ID:
307385433
4.

ATAC_H_E115-WT_rep1

Organism:
Mus musculus
Source name:
Embryonic Heart
Platform:
GPL21103
Series:
GSE232882 GSE232887
Download data: BW, NARROWPEAK
Sample
Accession:
GSM7385432
ID:
307385432
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Supplemental Content

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