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Items: 8

1.

Rapid PTEFb-dependent transcriptional reorganization underpins the glioma adaptive response to radiotherapy [ChIP-Seq]

(Submitter supplied) Using a combination of ChIP-, ATAC-, RNA-seq, and CUT&RUN in model systems of diffuse intrinsic pontine glioma and other pediatric high-grade gliomas, we observe a rapid genome-wide reorganization of active chromatin within hours of exposure to therapeutic ionizing radiation. This redistribution facilitates PTEFb-mediated pause-release of Pol II to drive nascent transcriptional induction of canonical DNA damage response programs. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL24676
6 Samples
Download data: BW
Series
Accession:
GSE227796
ID:
200227796
2.

Illumina NovaSeq 6000 (Homo sapiens)

Platform
Accession:
GPL24676
ID:
100024676
3.

Histone_3_K27_acetylation, DIPG4, AZD4573, radiation, replicate 2

Organism:
Homo sapiens
Source name:
DIPG4
Platform:
GPL24676
Series:
GSE227796 GSE227797
Download data: BW
Sample
Accession:
GSM7108312
ID:
307108312
4.

Histone_3_K27_acetylation, DIPG4, AZD4573, radiation, replicate 1

Organism:
Homo sapiens
Source name:
DIPG4
Platform:
GPL24676
Series:
GSE227796 GSE227797
Download data: BW
Sample
Accession:
GSM7108311
ID:
307108311
5.

Histone_3_K27_acetylation, DIPG4, DMSO, radiation, replicate 2

Organism:
Homo sapiens
Source name:
DIPG4
Platform:
GPL24676
Series:
GSE227796 GSE227797
Download data: BW
Sample
Accession:
GSM7108310
ID:
307108310
6.

Histone_3_K27_acetylation, DIPG4, DMSO, radiation, replicate 1

Organism:
Homo sapiens
Source name:
DIPG4
Platform:
GPL24676
Series:
GSE227796 GSE227797
Download data: BW
Sample
Accession:
GSM7108309
ID:
307108309
7.

Histone_3_K27_acetylation, DIPG4, DMSO, replicate 2

Organism:
Homo sapiens
Source name:
DIPG4
Platform:
GPL24676
Series:
GSE227796 GSE227797
Download data: BW
Sample
Accession:
GSM7108308
ID:
307108308
8.

Histone_3_K27_acetylation, DIPG4, DMSO, replicate 1

Organism:
Homo sapiens
Source name:
DIPG4
Platform:
GPL24676
Series:
GSE227796 GSE227797
Download data: BW
Sample
Accession:
GSM7108307
ID:
307108307
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Supplemental Content

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